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Air Filters for Childhood Asthma (DAISY Trial)

N/A
Recruiting
Led By Anjum Hajat, PhD, MPH
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age between 6-17 years
Poorly controlled physician diagnosed asthma defined as more than four days with asthma symptoms in the past two weeks, use of asthma rescue medication for more than four days in the past two weeks, or health care utilization due to asthma in the past year (hospitalization, emergency room visit, or unscheduled clinic visit)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up fev1 measures will be taken daily, once in the morning and once at night for the six week study time frame. prior to the six month follow up we will ask participants to take three consecutive days of fev1 measurements, for an additional 6 measures
Awards & highlights

Summary

"This trial aims to see if using box fans with filters can help reduce asthma symptoms and improve indoor air quality in children aged 6 to 17 with asthma in the Duwamish Valley, Seattle

Who is the study for?
This trial is for children aged 6-17 with asthma in the Duwamish Valley. They must be able to fill out questionnaires, use a peak flow meter, and have an air monitor at home. Details on specific inclusion or exclusion criteria are not provided.
What is being tested?
The study tests if box fans with MERV 13 filters versus sham (fake) filters can lessen asthma symptoms and improve lung function (FEV1) in asthmatic children by comparing indoor air quality and health outcomes between the two groups.
What are the potential side effects?
Since this trial involves non-invasive interventions like air filters, significant side effects are not expected. However, any unexpected reactions related to the intervention will be monitored.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 6 and 17 years old.
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My asthma symptoms have been frequent and severe recently.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~fev1 measures will be taken daily, once in the morning and once at night for the six week study time frame. prior to the six month follow up we will ask participants to take three consecutive days of fev1 measurements, for an additional 6 measures
This trial's timeline: 3 weeks for screening, Varies for treatment, and fev1 measures will be taken daily, once in the morning and once at night for the six week study time frame. prior to the six month follow up we will ask participants to take three consecutive days of fev1 measurements, for an additional 6 measures for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Asthma symptoms
FEV1
Secondary study objectives
Asthma quality of life
Health care utilization in the past month
Use of rescue medications

Trial Design

2Treatment groups
Experimental Treatment
Group I: Sham filterExperimental Treatment1 Intervention
Participants in this arm will receive a sham filter for their box fans. These filters receive a MERV rating of 1 and only filter very large particles and debris such as lint, hair and insects. These particles have little to no impact on asthma symptoms. MERV stands for "minimum efficiency reporting value" and a filter receives a MERV rating as determined by the American Society of Heating, Refrigeration, and Air-Conditioning Engineers.
Group II: MERV 13 filterExperimental Treatment1 Intervention
Participants in this arm will receive a MERV 13 filter for their box fans. MERV 13 filters trap the majority of small particles, as small as 1 micron. It also traps up to 75% of particles that are as small as 0.3 microns.

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Who is running the clinical trial?

National Institute of Environmental Health Sciences (NIEHS)NIH
290 Previous Clinical Trials
1,232,877 Total Patients Enrolled
1 Trials studying Childhood Asthma
126 Patients Enrolled for Childhood Asthma
University of WashingtonLead Sponsor
1,801 Previous Clinical Trials
1,908,770 Total Patients Enrolled
Anjum Hajat, PhD, MPHPrincipal InvestigatorUniversity of Washington
~53 spots leftby Jul 2028
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