Cognitive Integrated Motor Training for Mild Cognitive Impairment
(CM Trial)

Recruiting in Palo Alto (17 mi)

Overseen byKiran Karunakaran, PhD

Age: 65+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Kessler Foundation

No Placebo Group

Trial Summary

What is the purpose of this trial?

Problems with walking and balance are common in older adults with mild cognitive impairment. Walking and balance problems limit independence and increase risk for injuries due to falls. The purpose of this research study is to test the effectiveness of training that combines moving and thinking tasks, referred to as Personalized cognitive integrated sensorimotor virtual reality (VR)/mixed reality (MR) training on walking and balance ability. The study will also help to understand the changes in thinking ability and brain activity as a result of this training in older adults with mild cognitive impairment. The study will evaluate the differences between two intervention groups (n=20 each): 1) personalized cognitive integrated sensorimotor VR/MR training (CM), and 3) standard of care (CTRL) on gait, balance, community ambulation, and cognitive functions, as well as underlying biomechanical and neurophysiological mechanisms to understand the changes due to CM.

Eligibility Criteria

This trial is for older adults with mild cognitive impairment who have issues with walking and balance. Participants should be able to perform basic tasks independently but may be at risk of falls due to their condition.

Inclusion Criteria

I am between 65 and 85 years old.

Medical clearance will be obtained from a clinician or study team clinician if participant's physician is unavailable

I can understand and follow instructions for using a medical device.

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Exclusion Criteria

I experience double vision or involuntary eye movements.

I am not taking steroids, benzodiazepines, or neuroleptics.

My seizures are not under control.

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Treatment Details

Interventions

Personalized cognitive-sensorimotor VR/MR training (Behavioural Intervention)

Trial OverviewThe study tests a new training that combines physical movement and thinking tasks using virtual/mixed reality, aiming to improve gait and balance. It compares this method against the standard care given for such conditions.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: Personalized cognitive-sensorimotor VR/MR trainingExperimental Treatment1 Intervention

Thinking task integrated walking and balance training program

Group II: Standard of CareActive Control1 Intervention

Standard walking and balance training