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Behavioural Intervention

Cognitive Integrated Motor Training for Mild Cognitive Impairment (CM Trial)

N/A
Waitlist Available
Led By Kiran Karunakaran
Research Sponsored by Kessler Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Able to stand for 5 minutes
Be older than 65 years old
Must not have
Diplopia or nystagmus
Uncontrolled or unstable seizure disorder
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to test a new training program that combines movement and thinking tasks using virtual reality technology to improve walking and balance in older adults with mild cognitive impairment. The study will compare the effects of this

Who is the study for?
This trial is for older adults with mild cognitive impairment who have issues with walking and balance. Participants should be able to perform basic tasks independently but may be at risk of falls due to their condition.
What is being tested?
The study tests a new training that combines physical movement and thinking tasks using virtual/mixed reality, aiming to improve gait and balance. It compares this method against the standard care given for such conditions.
What are the potential side effects?
Since the intervention involves VR/MR training, potential side effects might include dizziness or nausea related to motion sickness, fatigue from physical activity, or discomfort from wearing VR equipment.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can stand for at least 5 minutes without help.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I experience double vision or involuntary eye movements.
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My seizures are not under control.
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I have uncontrolled low blood pressure when standing.
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I have a nerve or muscle condition that affects my ability to walk.
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I have had a leg injury or condition in the last 6 months that stops me from walking or standing.
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My body weight is over 135 kgs.
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I have severe stiffness or tightness in my ankle that limits its movement.
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I have a condition that affects how my legs work or align when I stand.
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I have a history of serious heart conditions.
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I can walk faster than 0.8 meters per second.
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I have a medical condition that makes MRI unsafe for me.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
10 Meter walk test
Balance
Berg balance Assessment
+14 more
Secondary study objectives
6 Minute Walk Test
Dynamic Gait Index (DGI)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Personalized cognitive-sensorimotor VR/MR trainingExperimental Treatment1 Intervention
Thinking task integrated walking and balance training program
Group II: Standard of CareActive Control1 Intervention
Standard walking and balance training

Find a Location

Who is running the clinical trial?

Kessler FoundationLead Sponsor
183 Previous Clinical Trials
11,093 Total Patients Enrolled
Rutgers UniversityOTHER
121 Previous Clinical Trials
2,809,314 Total Patients Enrolled
New Jersey Institute of TechnologyOTHER
10 Previous Clinical Trials
1,045 Total Patients Enrolled
Kiran KarunakaranPrincipal InvestigatorKessler Foundation
1 Previous Clinical Trials
30 Total Patients Enrolled
~27 spots leftby Aug 2027