← Back to Search

Insulin

United States Coronary Artery Bypass Surgery (CABG) Diabetes Project (USCDP) Pilot Study (USCDP Trial)

N/A
Waitlist Available
Led By Anthony Furnary, MD
Research Sponsored by Providence Heart & Vascular Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

Standard care for patients with diabetes having CABG surgery at Providence St. Vincent Medical Center includes strict control of blood sugar (glucose) levels for 3 days after surgery. This is done through frequent monitoring of blood sugar levels and by giving insulin continuously through a needle into a vein (intravenously). This intensive glucose control has resulted in fewer complications such as serious infections and death, and has shortened the length of the hospital stay for patients. This study treatment is different from standard treatment in that it extends the intensive glucose control beyond the third postoperative day to one full year. Once discharged from the hospital following the CABG procedure, the intense glucose control is done using subcutaneous insulin (a shot under the skin), oral medications, and by measuring blood sugar levels frequently. The purpose of this study is to see how safe and effective strict glucose control is when extended beyond 3 days and hospital discharge for one year. Another purpose is to see how well patients can comply with the daily management of intensive glucose control for one-year as well as the study follow-up schedule.

Eligible Conditions
  • Coronary Artery Disease
  • Diabetes

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: 1Active Control1 Intervention
strict glucose control (study arm)
Group II: 2Active Control1 Intervention
standard insulin treatment (control arm)

Find a Location

Who is running the clinical trial?

Providence Heart & Vascular InstituteLead Sponsor
1 Previous Clinical Trials
500 Total Patients Enrolled
SanofiIndustry Sponsor
2,215 Previous Clinical Trials
4,046,960 Total Patients Enrolled
14 Trials studying Coronary Artery Disease
41,613 Patients Enrolled for Coronary Artery Disease
LifeScanIndustry Sponsor
33 Previous Clinical Trials
19,539 Total Patients Enrolled
Anthony Furnary, MDPrincipal InvestigatorProvidence Heart & Vascular Institute
1 Previous Clinical Trials
230 Total Patients Enrolled
~7 spots leftby Dec 2025