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Behavioural Intervention

Web-based Sleep Interventions for Caregiver Insomnia (NiteCAPP Trial)

N/A
Recruiting
Led By Christina S McCrae
Research Sponsored by University of Missouri-Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up daily at baseline, 8 weeks, 6 month and 12 follow up
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing whether a web-based sleep intervention will help rural caregivers of people with dementia, by improving sleep, arousal, stress, inflammation, and related health concerns.

Who is the study for?
This trial is for adult caregivers living with someone who has dementia and insomnia. Caregivers must have their own insomnia diagnosis, not be on recent sleep meds, and read English. The person with dementia must also suffer from insomnia but can't be on new sleep meds or have untreated sleep disorders like severe apnea.
What is being tested?
The NiteCAPP study tests two web-based programs (CARES & SHARES) designed to help rural caregivers of dementia patients manage insomnia. It looks at how well these programs work right after treatment and checks again after 6 and 12 months for any changes in the caregiver's sleep, health, mood, stress levels, and cognitive function.
What are the potential side effects?
Since this trial involves non-medical interventions like web-based programs focusing on behavioral strategies for managing insomnia, typical medication side effects are not expected. However, participants may experience frustration or discomfort if they find the technology challenging or if there's no improvement in their symptoms.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~daily at baseline, 8 weeks, 6 month and 12 follow up
This trial's timeline: 3 weeks for screening, Varies for treatment, and daily at baseline, 8 weeks, 6 month and 12 follow up for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Adherence
Change in Blood-based Biomarker AβB42
Interleukins
+17 more
Secondary study objectives
Change in 36-Item Short Form Survey (SF-36)
Change in Caregiver Burden (Zarit Burden Scale)
Change in Cognitive Failures Questionnaire (CFQ)
+8 more
Other study objectives
Change in Dementia Severity Rating Scale
Change in Godin Leisure-Time Exercise Questionnaire
Change in Neuropsychiatric Inventory(NPI) Nighttime Behavior Scale
+2 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: NiteCAPP SHARESExperimental Treatment1 Intervention
Sleep Hygiene and Related Education. Web-based intervention that will include 4 weekly sessions and 4 bimonthly boosters. Each session is to be completed individually by CG (with PWD to extent able) in a single sitting (less than 45 mins). Each session should be completed in 7 days with next session released only after prior one completed. Session 1 focuses on expanded sleep education and sleep hygiene. Session 2 focuses insomnia education and sleep hygiene support. Session 3 focuses on targeted sleep education and sleep in dementia. Session 4 focuses on a review of skills and plan for maintenance of behavior change. Boosters review skills, encourage practice, and troubleshoot issues.
Group II: NiteCAPP CARESExperimental Treatment1 Intervention
Cognitive Behavioral Treatment-Insomnia. Web-based intervention that will include 4 weekly sessions and 4 bimonthly boosters. Each session is to be completed individually by CG (with PWD to extent able) in a single sitting (less than 45 mins). Each session should be completed in 7 days with next session released only after prior one completed. Session 1 focuses on sleep education, sleep hygiene, and stimulus control. Session 2 focuses on sleep compression, relaxation, and problem solving. Session 3 focuses on coping and stress management and cognitive therapy. Session 4 focuses on a review of skills and plan for maintenance of behavior change.

Find a Location

Who is running the clinical trial?

University of Missouri-ColumbiaLead Sponsor
380 Previous Clinical Trials
628,662 Total Patients Enrolled
1 Trials studying Dementia
60 Patients Enrolled for Dementia
University of South FloridaLead Sponsor
427 Previous Clinical Trials
192,531 Total Patients Enrolled
6 Trials studying Dementia
2,986 Patients Enrolled for Dementia
Christina S McCraePrincipal InvestigatorUniversity of South Florida

Media Library

NiteCAPP CARE (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04896775 — N/A
Dementia Research Study Groups: NiteCAPP CARES, NiteCAPP SHARES
Dementia Clinical Trial 2023: NiteCAPP CARE Highlights & Side Effects. Trial Name: NCT04896775 — N/A
NiteCAPP CARE (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04896775 — N/A
~31 spots leftby Mar 2026