← Back to Search

Behavioral Intervention

Digital Neurotherapy for Depression and Cognitive Improvement in Cancer Survivors

N/A

Waitlist Available

Led By Jennifer Kilkus, MD

Research Sponsored by Yale University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Have received chemotherapy, and/or radiation treatment, and/or immunotherapy treatment for cancer

Be older than 18 years old

Must not have

Hearing or vision insufficient to do the computer exercises.

Brain cancer

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 4 weeks, 8 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether a digital neurotherapy can help relieve depression, improve cognition, and quality of life in cancer survivors.

Who is the study for?

This trial is for adult cancer survivors from Smilow Cancer Hospital who have undergone chemotherapy, radiation, or immunotherapy. Participants must understand English and be willing to follow the study's procedures. Those with serious mental illness, cognitive impairment, severe hearing or vision issues, stage 4 cancer, or brain cancer cannot join.

What is being tested?

The study is testing a digital neurotherapy (DNT) treatment aimed at improving depression symptoms, cognition, and quality of life in cancer survivors. It's a randomized trial where participants are either placed in the DNT group or put on a wait list as a control.

What are the potential side effects?

Since this intervention involves non-invasive digital therapy rather than medication or surgery, significant side effects are not expected. However, participants may experience fatigue or discomfort from using digital devices.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have undergone chemotherapy, radiation, or immunotherapy for cancer.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

My hearing and vision allow me to do computer exercises.

Select...

I have brain cancer.

Select...

My cancer is at stage 4.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 4 weeks, 8 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 4 weeks, 8 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 4 weeks, 8 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in California Verbal Learning Test-II

Change in Controlled Oral Word Association Test

Change in Flanker Task

+8 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Digital neurotherapy (DNT) TreatmentExperimental Treatment1 Intervention

The experimental group will have 8 weeks of DNT 4 times a week for 30 minutes in the participant's home. The computer-presented training will be done on the participants' tablets or personal computers with the Rejuvenate brain training program

Group II: Wait list control groupActive Control1 Intervention

Waiting-list control group participants will be offered 8 weeks of DNT training at the completion of the final outcome assessment.

0 / 4Eligibility criteria met