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Non-invasive Brain Stimulation

Transcranial Magnetic Stimulation for Depression

N/A
Waitlist Available
Led By Joan Camprodon, MD, PhD, MPH
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through treatment completion, average of 6 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial looked at the effects of TMS on the brains of patients with unipolar depression.

Who is the study for?
This trial is for men and women aged 18-80 with a diagnosis of depression who need Transcranial Magnetic Stimulation (TMS) as part of their psychiatric care. It's not suitable for those with MRI contraindications, other primary mental health conditions like schizophrenia, active substance abuse in the past 3 months, or severe medical illnesses.
What is being tested?
The study observes how TMS affects the brain in patients with unipolar depression. This non-invasive treatment uses magnetic fields to stimulate nerve cells in the brain and is being studied using neuroimaging techniques.
What are the potential side effects?
While this observational study focuses on imaging results rather than side effects, TMS can sometimes cause headaches, scalp discomfort at the site of stimulation, tingling or spasms of facial muscles, lightheadedness or seizures (rare).

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through treatment completion, average of 6 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and through treatment completion, average of 6 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in Functional Connectivity of Key Nodes in Depression

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Unipolar DepressionExperimental Treatment1 Intervention
Patients diagnosed with unipolar depression.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation
2017
Completed Phase 4
~730

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
3,026 Previous Clinical Trials
13,413,745 Total Patients Enrolled
193 Trials studying Depression
34,108 Patients Enrolled for Depression
Joan Camprodon, MD, PhD, MPHPrincipal InvestigatorMassachusetts General Hospital
5 Previous Clinical Trials
930 Total Patients Enrolled
~1 spots leftby Apr 2025
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