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Math & Cognitive Skill Interventions for Dyscalculia

N/A

Recruiting

Research Sponsored by Stanford University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Normal or corrected-to-normal vision and no hearing impairments

Be younger than 18 years old

Must not have

History of trauma involving head injury

History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline and post-intervention (after 6 weeks)

Awards & highlights

No Placebo-Only Group

Summary

This trial looks at ways to help children with weak math skills, including those with MLD, to improve their numerical skills. #math #learningdisabilities

Who is the study for?

This trial is for elementary school children aged 6-12 with an IQ over 70. It's aimed at those struggling with math, scoring below the 25-35th percentile in certain tests, and typically developing kids who score above that range. Participants must have normal vision and hearing, be right-handed for MRI scans, and not have psychiatric disorders or head injuries.

What is being tested?

The study is testing educational interventions to improve mathematical skills in children with learning disabilities compared to typical development. It examines how these interventions affect brain function and decision-making related to numbers.

What are the potential side effects?

Since this trial involves educational interventions rather than medical treatments, traditional side effects are not applicable. However, participants may experience fatigue or stress from testing situations.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My vision is normal or corrected to normal, and I don't have hearing problems.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have had a head injury due to an accident or trauma.

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I have a history of mental health issues like schizophrenia or ADHD.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline and post-intervention (after 6 weeks)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline and post-intervention (after 6 weeks)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and post-intervention (after 6 weeks) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change from baseline in brain activation during non-symbolic number comparison task performance

Change from baseline in brain activation during symbolic number comparison task performance

Change from baseline in latent cognitive measures of non-symbolic number comparison task performance (drift rate)

+7 more

Secondary study objectives

Change from baseline in symbolic addition task performance (accuracy)

Change from baseline in symbolic addition task performance (reaction time)

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Integrative Symbolic Non-Symbolic (iSNS) TrainingExperimental Treatment1 Intervention

Integrative symbolic non-symbolic (iSNS) training: Over a period of 6 weeks, participants will complete activities that progressively strengthen the mapping of symbolic numerical representations to non-symbolic numerical quantities and enhance fluency in symbolic numerical skills.

Group II: Active Comparator: Active Control Intervention (Working Memory Training)Active Control1 Intervention

Active control intervention: Over a period of 6 weeks, participants will complete activities that enhance short-term storage and maintenance of visuospatial or verbal information.

0 / 3Eligibility criteria met