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Procedure

Brain Stimulation for Dyslexia

N/A
Recruiting
Research Sponsored by Georgia State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Normal or corrected to normal vision
Be younger than 65 years old
Must not have
Hearing deficits (>25 decibels at 500+ Hz), visual deficits (>20/40), serious emotional problems (e.g., severe, uncontrolled depression) and certain neurological conditions (e.g., uncontrolled seizure disorders)
Individuals taking certain medications that lower seizure threshold
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline

Summary

This trial aims to use a technique called transcranial magnetic stimulation (TMS) to study how older youth learn spoken words. The study will focus on how inhibiting a specific part of the brain

Who is the study for?
This trial is for older youth with dyslexia. Participants should be able to undergo brain stimulation and are interested in how it might affect learning new spoken words. Specific eligibility details aren't provided, so generally healthy individuals who meet the age requirement for 'older youth' may apply.
What is being tested?
The study tests if a type of brain stimulation called cTBS can influence learning, processing, and remembering made-up words that sound similar. Some participants will receive real cTBS while others get a sham (fake) treatment to compare results.
What are the potential side effects?
While specific side effects are not listed, TMS can sometimes cause discomfort at the stimulation site, headache, lightheadedness or seizures in very rare cases.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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My vision is normal or corrected to normal with glasses or contacts.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I do not have severe hearing, vision, emotional, or uncontrolled neurological conditions.
Select...
I am taking medication that could increase my risk of seizures.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5-mins post stimulation; 24hrs post stimulation
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5-mins post stimulation; 24hrs post stimulation for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Novel Word Learning Task
Pseudoword Discrimination Task
Secondary study objectives
MRI Scan

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Active cTBSExperimental Treatment1 Intervention
Active cTBS will be administered to the left supramarginal gyrus
Group II: Sham stimulationPlacebo Group1 Intervention
Sham stimulation will be administered to the left supramarginal gyrus

Find a Location

Who is running the clinical trial?

Georgia State UniversityLead Sponsor
65 Previous Clinical Trials
30,666 Total Patients Enrolled
2 Trials studying Dyslexia
478 Patients Enrolled for Dyslexia
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH
2,068 Previous Clinical Trials
2,747,504 Total Patients Enrolled
10 Trials studying Dyslexia
6,054 Patients Enrolled for Dyslexia
~19 spots leftby Oct 2025
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