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Study EC + VLNC CC for Nicotine Addiction

N/A
Waitlist Available
Led By Francis McClernon, Ph.D.
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during preference session, approximately 2 hours
Awards & highlights

Study Summary

This trialwill investigate how reducing nicotine in cigarettes affects smokers' choices between regular cigarettes & e-cigarettes.

Eligible Conditions
  • Nicotine Addiction
  • Smoking/Cigarette Smoking
  • Electronic Cigarette Use
  • Smoking

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during preference session, approximately 2 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and during preference session, approximately 2 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of choices for CC during preference task
Secondary outcome measures
CO boost
Cigarette Evaluation Scale
Craving
+5 more

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Study EC + VLNC CCExperimental Treatment2 Interventions
Participants will make choices between the study EC device with tobacco flavor and the very low nicotine content (VLNC) investigational CC
Group II: Study EC + NNC CCActive Control2 Interventions
Participants will make choices between the study EC device with tobacco flavor and the normal nicotine content (NNC) investigational CC
Group III: Own EC + UB CCActive Control1 Intervention
Participants will make choices between their own EC device with their own tobacco flavor and their UB CC
Group IV: Study EC + UB CCActive Control1 Intervention
Participants will make choices between the study e-cigarette (EC) device with tobacco flavor and their usual brand (UB) combusted cigarette (CC)

Find a Location

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,488 Previous Clinical Trials
2,622,645 Total Patients Enrolled
15 Trials studying Nicotine Addiction
2,130 Patients Enrolled for Nicotine Addiction
National Institutes of Health (NIH)NIH
2,720 Previous Clinical Trials
7,494,267 Total Patients Enrolled
3 Trials studying Nicotine Addiction
327 Patients Enrolled for Nicotine Addiction
Duke UniversityLead Sponsor
2,381 Previous Clinical Trials
3,427,544 Total Patients Enrolled
3 Trials studying Nicotine Addiction
164 Patients Enrolled for Nicotine Addiction
~3 spots leftby Jun 2025
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