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Behavioural Intervention
Electronic Hookah and Endothelial Cell Function
N/A
Waitlist Available
Led By Mary Rezk-Hanna, PhD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up changes pre- and post- the 30-minute smoking or vaping exposure sessions
Awards & highlights
No Placebo-Only Group
Summary
This trial focuses on adolescents and young adults who use e-hookahs. E-hookahs create vapor from a liquid containing nicotine and other substances, which is inhaled through a water pipe. The study aims to understand how this vapor affects blood vessel function, especially the role of nicotine.
Eligible Conditions
- Endothelial Dysfunction
- Smoking
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ changes pre- and post- the 30-minute smoking or vaping exposure sessions
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~changes pre- and post- the 30-minute smoking or vaping exposure sessions
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Acetylcholine-stimulated nitric oxide production
Basal reactive oxygen species bioactivity
Carbon monoxide levels
+6 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Group I: e-hookah vaping without nicotineExperimental Treatment2 Interventions
Participants were invited to vape a 30-minute electronic hookah without nicotine vaping session, followed by a 30-minute electronic hookah with nicotine vaping session.
To mitigate the impact of carryover effects, the two sessions were separated by a minimum of 7-days.
Group II: e-hookah vaping with nicotineExperimental Treatment2 Interventions
Participants were invited to vape a 30-minute electronic hookah with nicotine vaping session, followed by a 30-minute electronic hookah without nicotine vaping session.
To mitigate the impact of carryover effects, the two sessions were separated by a minimum of 7-days.
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Who is running the clinical trial?
University of California, Los AngelesLead Sponsor
1,567 Previous Clinical Trials
10,266,967 Total Patients Enrolled
5 Trials studying Endothelial Dysfunction
346 Patients Enrolled for Endothelial Dysfunction
Tobacco Related Disease Research ProgramOTHER
26 Previous Clinical Trials
26,362 Total Patients Enrolled
Mary Rezk-Hanna, PhDPrincipal Investigator - University of California, Los Angeles
University of California, Los Angeles