e-hookah vaping with nicotine for Endothelial Dysfunction

N/A

Waitlist Available

Led By Mary Rezk-Hanna, PhD

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up changes pre- and post- the 30-minute smoking or vaping exposure sessions

Awards & highlights

No Placebo-Only Group

Summary

This trial focuses on adolescents and young adults who use e-hookahs. E-hookahs create vapor from a liquid containing nicotine and other substances, which is inhaled through a water pipe. The study aims to understand how this vapor affects blood vessel function, especially the role of nicotine.

Eligible Conditions

Endothelial Dysfunction
Smoking

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ changes pre- and post- the 30-minute smoking or vaping exposure sessions

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~changes pre- and post- the 30-minute smoking or vaping exposure sessions

This trial's timeline: 3 weeks for screening, Varies for treatment, and changes pre- and post- the 30-minute smoking or vaping exposure sessions for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Acetylcholine-stimulated nitric oxide production

Basal reactive oxygen species bioactivity

Carbon monoxide levels

+6 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Group I: e-hookah vaping without nicotineExperimental Treatment2 Interventions

Participants were invited to vape a 30-minute electronic hookah without nicotine vaping session, followed by a 30-minute electronic hookah with nicotine vaping session. To mitigate the impact of carryover effects, the two sessions were separated by a minimum of 7-days.

Group II: e-hookah vaping with nicotineExperimental Treatment2 Interventions

Participants were invited to vape a 30-minute electronic hookah with nicotine vaping session, followed by a 30-minute electronic hookah without nicotine vaping session. To mitigate the impact of carryover effects, the two sessions were separated by a minimum of 7-days.

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