Targeting Inflammation for Endometrial Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore how chronic inflammation might increase the risk of developing endometrial cancer. Researchers will collect blood, urine, and tissue samples, along with a questionnaire, to better understand this potential link. It suits women undergoing a hysterectomy due to benign conditions or endometrial cancer. By providing these samples and information, participants will help identify prevention strategies for this type of cancer. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could lead to new prevention strategies for endometrial cancer.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to explore the role of inflammation in preventing endometrial cancer through non-invasive means. Unlike traditional treatments that focus on removing or targeting cancer cells, this study focuses on understanding risk factors and biological markers by collecting blood, urine, and tissue samples. By identifying these markers, scientists hope to develop preventative strategies that could reduce the risk of developing endometrial cancer before it starts. This approach has the potential to shift the focus from treatment to prevention, offering a new avenue for reducing cancer incidence.
Who Is on the Research Team?
Mark E. Sherman, M.D.
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-operative Visit
Participants complete a risk factor questionnaire and undergo collection of blood and urine
Surgery
Collection of tissue samples at the time of surgery
Follow-up
Participants are monitored for RNA expression pathways and levels of eicosanoids and SPMs
What Are the Treatments Tested in This Trial?
Interventions
- Biospecimen Collection
- Questionnaire Administration
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Patients complete a risk factor questionnaire over 15 minutes. Patients also undergo collection of blood and urine during pre-operative visit and collection of tissue samples at the time of surgery.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
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