Aerobic Exercise for Gut Health (FITGut-W Trial)

N/A

Recruiting

Research Sponsored by George Washington University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

BMI 19 to 24.99 kg/m2 or BMI 30-40 kg/m2

Biological sex: female

Must not have

Biological sex: male

Currently pregnant, < 2 years postpartum, lactating

Timeline

Screening 3 weeks

Treatment Varies

Follow Up before the exercise intervention and immediately after the intervention

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to study the differences in the gut microbiome and metabolites in adult women with different fitness levels and BMIs. They want to see how a 30-minute aerobic exercise session affects the

Who is the study for?

This trial is for premenopausal women with varying fitness levels and body sizes, specifically including those who are obese. Participants should be interested in how a single session of aerobic exercise can affect their gut bacteria.

What is being tested?

The study is testing the impact of a 30-minute aerobic workout at moderate intensity (60-70% heart rate reserve) on the gut microbiome's function and metabolites in blood and stool, focusing on short-chain fatty acid production.

What are the potential side effects?

Since this trial involves moderate exercise, potential side effects may include muscle soreness, fatigue, or mild discomfort during or after the workout. No severe side effects are expected.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My BMI is either between 19-24.99 or 30-40.

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I am female.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am male.

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I am currently pregnant, less than 2 years postpartum, or breastfeeding.

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I am currently taking herbal, fiber, or prebiotic supplements.

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I have been diagnosed with a disease related to the stomach, hormones, digestion, cancer, or heart.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ before the exercise intervention, immediately after the exercise intervention, and 24 hours before the intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~before the exercise intervention, immediately after the exercise intervention, and 24 hours before the intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and before the exercise intervention, immediately after the exercise intervention, and 24 hours before the intervention for reporting.