Popular Trials
Bacterial Extract
Oral Bacterial Extract for Wheezing
This trial tests if giving Broncho-Vaxom® to high-risk infants can delay their first episode of wheezing illness. The medication is given regularly over a long period and aims to boost the immune system. The study focuses on infants aged 6-18 months who are more likely to develop asthma.
Alkylating agents
Genotype-Directed Chemotherapy for Colorectal Cancer
This trial is testing a new way to give colon cancer patients a standard combination chemotherapy treatment, which includes the anti-cancer drugs 5-Fluorouracil (5FU), leucovorin and irinotecan (known as FOLFIRI), plus the anti-angiogenesis drug bevacizumab (Avastin). The study is designed to test the FOLFIRI regimen based on certain characteristics of a person's genetic makeup or "genes".
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Trials for HIV Patients
Antiretroviral
E/C/F/TAF for HIV-1 Infection
This trial tests a single pill combining four HIV medications in adolescents and children. It aims to find the right dose and ensure safety for those new to treatment and those already on it. The pill works by stopping the virus from growing and spreading.
Nucleoside/nucleotide reverse transcriptase inhibitor
F/TAF for HIV-Controlled Pediatric Patients
This trial is studying the safety and effectiveness of a new HIV drug in children and adolescents who are already taking other HIV drugs and have had their HIV infection controlled for at least six months.
Trials for Cancer Patients
Cannabinoid
Medical Cannabis for Chronic Pain
This trial will investigate if medical cannabis can effectively reduce pain and improve quality of life for patients with chronic conditions. The study will gather data through an online questionnaire about patients' use of cannabis and its effects. Medical cannabis interacts with the body's natural system to help manage pain and other symptoms. Medical cannabis has been increasingly studied and used as an alternative treatment for managing chronic pain, with numerous studies supporting its potential benefits.
Alkylating agents
Lurbinectedin + Irinotecan for Cancer
This trial is testing a new cancer drug, Lurbinectedin, in combination with another cancer drug, irinotecan. The trial will have two parts: first, they will test different doses of the drugs to see what is safe; then, they will expand the trial to include more people.
Checkpoint Inhibitor
Nivolumab for Esophageal Cancer
This trial is testing if Nivolumab, a drug that helps the immune system fight cancer, can help cancer patients stay free of the disease longer. Nivolumab has been shown to improve survival in various cancers, including melanoma and esophageal cancer.
Phase 3 Trials
Antiretroviral
E/C/F/TAF for HIV-1 Infection
This trial tests a single pill combining four HIV medications in adolescents and children. It aims to find the right dose and ensure safety for those new to treatment and those already on it. The pill works by stopping the virus from growing and spreading.
Nucleoside/nucleotide reverse transcriptase inhibitor
F/TAF for HIV-Controlled Pediatric Patients
This trial is studying the safety and effectiveness of a new HIV drug in children and adolescents who are already taking other HIV drugs and have had their HIV infection controlled for at least six months.
Trials With No Placebo
Cannabinoid
Medical Cannabis for Chronic Pain
This trial will investigate if medical cannabis can effectively reduce pain and improve quality of life for patients with chronic conditions. The study will gather data through an online questionnaire about patients' use of cannabis and its effects. Medical cannabis interacts with the body's natural system to help manage pain and other symptoms. Medical cannabis has been increasingly studied and used as an alternative treatment for managing chronic pain, with numerous studies supporting its potential benefits.
Alkylating agents
Risk-Directed Therapy for Medulloblastoma
This trial will use a new way to treat medulloblastoma, which is a cancer of the brain. The treatment will be based on the amount of leftover disease present after surgery, as well as the type of cancer cells. This will help to determine the best way to treat the cancer and improve the outcome for patients.
Antiretroviral
E/C/F/TAF for HIV-1 Infection
This trial tests a single pill combining four HIV medications in adolescents and children. It aims to find the right dose and ensure safety for those new to treatment and those already on it. The pill works by stopping the virus from growing and spreading.
Procedure
3-Tesla MRI for Prostate Cancer
This trial is testing whether an MRI of the prostate done with a 3 Tesla magnet and an external body coil is as good as the standard 1.5 Tesla MRI with an endorectal coil in terms of helping doctors decide which approaches to disease therapy might be best for patients.
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Frequently Asked Questions
Introduction to cte
What are the top hospitals conducting cte research?
Chronic Traumatic Encephalopathy (CTE) is a complex neurodegenerative condition that has gained significant attention in recent years due to its association with repeated head injuries, particularly in contact sports. In the quest for understanding and finding effective treatments for CTE, top hospitals are leading the way in conducting clinical trials. Among these institutions is the esteemed Dana-Farber Cancer Institute based in Boston. With five ongoing CTE trials, they are at the forefront of research into this debilitating condition. Similarly, Memorial Sloan Kettering Cancer Center in New york also prioritizes CTE research with an equal number of active trials aimed at unraveling the complexities surrounding this disorder.
Adding to these efforts is Tufts Medical Center, another renowned hospital located in Boston, where four active clinical trials focusing on CTE are currently underway. Not limited to just one region, two other notable locations involved in combating CTE through clinical research include a Research Site based out of New York and another situated in Montreal—each contributing three ongoing clinical trials dedicated to uncovering new insights about this challenging condition.
It's important to note that while these hospitals have made significant contributions by initiating several active studies related to CTE treatment and understanding; there hasn't been any recorded completed trial as yet highlighting how crucial it remains for further exploration into potential interventions or preventive measures against this progressive neurological disorder affecting individuals exposed to repetitive brain trauma.
The dedication shown by these institutions reflects their commitment not only toward alleviating the suffering caused by CTE but also fostering scientific progress that could reshape our approach towards preventing long-term consequences associated with traumatic brain injuries. By driving forward innovative research initiatives focused on improving our knowledge surrounding chronic traumatic encephalopathy, they offer hope for future generations impacted by head trauma and inspire collective efforts aimed at safeguarding athletes' well-being worldwide
Which are the best cities for cte clinical trials?
When it comes to clinical trials for chronic traumatic encephalopathy (CTE), several cities emerge as top contenders in research and development. New york, with 30 active trials, focuses on investigating treatments like Pembrolizumab and SRS, PF-07062119, among others. Los Angeles follows closely behind with 19 ongoing studies exploring interventions such as Durvalumab, Abemaciclib, and patients diagnosed with pulmonary arterial hypertension (PAH) or CTEPH. Atlanta boasts 17 active trials examining options like palliative radiation therapy, Maraviroc, ALIS, and more. Lastly, Chicago offers 16 active trials that delve into treatments including oral Cabotegravir (CAB), Durvalumab, Trastuzumab deruxtecan. Together these cities provide access to cutting-edge clinical trials for individuals battling CTE across the United States.
Which are the top treatments for cte being explored in clinical trials?
Clinical trials are actively exploring several promising treatments for Chronic Traumatic Encephalopathy (CTE). The top contenders in these trials include:
- Treatment A: Currently being tested in X number of active CTE trials and Y number of all-time clinical trials.
- Treatment B: Under investigation in Z number of ongoing CTE studies and W number of all-time clinical trials.
- Treatment C: Showing potential with Q number of active CTE trials and R number of all-time clinical trials.
These innovative treatments offer hope for those affected by this debilitating condition, as researchers continue their relentless pursuit to find effective therapies for CTE.
What are the most recent clinical trials for cte?
Promising developments in clinical trials offer hope for those affected by chronic traumatic encephalopathy (CTE). One significant trial involves ASKG915, a potential treatment currently undergoing Phase 1 testing. Additionally, LB2102 is an experimental therapy showing promise in its Phase 1 trial for CTE patients. Immunotherapy has also emerged as a potential avenue, with the combination of avelumab and lurbinectedin being evaluated during Phase 2 trials. The TAK-861 Dose 1 trial has advanced to both Phase 2 and Phase 3 stages, offering further possibilities for effective CTE treatments. These recent clinical trials provide optimism that innovative therapies will soon be available to improve the lives of individuals living with CTE.
What cte clinical trials were recently completed?
Recently completed clinical trials for chronic traumatic encephalopathy (CTE) are paving the way for enhanced understanding and potential treatments of this debilitating condition. Notably, a trial sponsored by Washington University School of Medicine was concluded in October 2021, focusing on addressing key aspects of CTE. The dedication to research is evident as scientists strive to unlock new insights into the complexities of CTE and develop strategies that could bring hope to individuals affected by this neurodegenerative disease.