Botulinum Toxin A for Facial Flushing

Recruiting in Palo Alto (17 mi)

Overseen byMurad Alam, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 4

Waitlist Available

Sponsor: Northwestern University

Prior Safety Data

Trial Summary

What is the purpose of this trial?

The purpose of this study is to find out if botulinum toxin A (botox®) can be used to treat facial flushing. This study is a pilot study designed to determine feasibility of these procedures.

Research Team

Murad Alam, MD

Principal Investigator

Northwestern University

Eligibility Criteria

This trial is for adults aged 18-65 who experience persistent facial flushing and can give informed consent. It's not suitable for those with certain medical conditions like heart failure, bleeding disorders, or allergies to botox ingredients. Pregnant women, people on specific medications, or those who've had recent cosmetic treatments in the face are excluded.

Inclusion Criteria

Willing and have the ability to understand and provide informed consent for participation in the study and are able to communicate with the study staff.

You are between 18 and 65 years old and experience ongoing redness in your face.

Exclusion Criteria

You have had congestive heart failure, carcinoid syndrome, mastocystosis, or renal cell carcinoma in the past.

You have received a radiofrequency device treatment in the past 6 months.

You have had problems with bleeding in the past.

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Treatment Details

Interventions

Botulinum Toxin A (Neurotoxin)

Trial OverviewThe study is testing whether botulinum toxin A (Botox®) injections can help treat facial flushing compared to a saline control. This pilot study aims to assess the feasibility of using Botox for this purpose.

Participant Groups

2Treatment groups

Experimental Treatment

Placebo Group

Group I: botulinum toxin AExperimental Treatment1 Intervention

This study is randomized, which means the subject will be randomly assigned (like a flip of a coin) to receive botox on the right or left side of the face and saline injections on the other side. Only one side of the face will receive botox injections.

Group II: Saline ControlPlacebo Group1 Intervention