Trial Summary
What is the purpose of this trial?This trial compares standard care to a spinal injection for kidney stone pain. The injection aims to block pain signals and provide relief. Pain levels will be measured over time after the injection.
What data supports the idea that ESP Block for Kidney Stones is an effective treatment?The available research shows that the Erector Spinae Plane Block (ESPB) is effective in reducing pain after kidney stone procedures. One study found that ESPB provided better pain relief compared to a placebo in patients who had undergone a procedure to remove kidney stones. Another case series showed that ESPB significantly improved pain in patients with acute kidney stone pain, suggesting it can be a safe and effective treatment option. These findings indicate that ESPB can help manage pain effectively for kidney stone patients.24567
Do I need to stop my current medications to join the trial?The trial protocol does not specify whether you need to stop taking your current medications.
Is the Erector Spinae Plane Block a promising treatment for kidney stones?Yes, the Erector Spinae Plane Block (ESPB) is a promising treatment for kidney stones. It is shown to provide effective pain relief after kidney stone surgeries and for acute pain from kidney stones. It is simple, safe, and has a lower complication rate compared to other methods, making it a good option for pain management.14578
What safety data exists for ESP Block in treating kidney stones?The Erector Spinae Plane (ESP) block is considered a safe interfascial plane block with a lower risk of neurovascular and pleural injury compared to epidural or paravertebral blocks. It is noted for its easy sonographic identification and lower complication rate, making it a popular choice in regional anesthesia. Although specific safety data for kidney stones is limited, its application in similar procedures like percutaneous nephrolithotomy (PCNL) and other abdominal surgeries suggests a favorable safety profile.13568
Eligibility Criteria
This trial is for adults aged 18 to 65 who are experiencing flank pain due to kidney stones and are in the emergency department. They should be generally healthy without serious heart, lung, liver, or kidney problems. Pregnant women and those with allergies to local anesthetics like Ropivacaine can't join. Also excluded are individuals with a history of spine issues or mental disease exacerbations.Treatment Details
The study is examining if injecting Ropivacaine (an anesthetic) near the spine (ESP block) is better at managing acute pain from kidney stones compared to standard medications alone. Participants will either receive this injection along with standard care or just the standard treatment.
2Treatment groups
Active Control
Group I: ESP Nerve Block for Renal colicActive Control1 Intervention
On top of receiving standard of care, At T8 nerve level, with ultrasound guidance to bathe the nerve
Group II: Standard of careActive Control1 Intervention
Whatever medications the clinician normally treats renal colic with
Find a clinic near you
Research locations nearbySelect from list below to view details:
StonyBrook University HospitalStony Brook, NY
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Who is running the clinical trial?
Stony Brook UniversityLead Sponsor
References
Relief of refractory renal colic in emergency department: A novel indication for ultrasound guided erector spinae plane block. [2019]Plane blocks have become very popular in recent years with the introduction of ultrasonography into the regional anesthesia and algology practice. Erector spinae plane (ESP) block involves injection of local anesthetics between erector spinae muscles and transverse process of vertebrae and can block the dorsal and ventral rami of thoracolumbar spinal nerves. The primary factor in the great popularity of this block is easy sonographic identification of landmarks and lower complication rate compared to paravertebral or central neuroaxial blocks. These characteristics mean that it will in all probability be widely used in the future, not just for anesthetists, but also for emergency physicians. Here we first report a novel indication for ESP block in emergency department; renal colic.
Postoperative Pain Relief Following Lumbar Erector Spinae Plane Block in Patients Undergoing Percutaneous Nephrolithotomy: A Randomized Controlled Trial. [2022]To test whether lumbar Erector Spinae Plane Block (ESPB) provides superior analgesia compared to placebo in patients undergoing Percutaneous Nephrolithotomy (PCNL), using reduction in postoperative opioid consumption, delay in rescue analgesia demand and reduction of pain scores as outcome measures.
Efficacy of bilateral erector spinae block for post-operative analgesia in liver hydatid surgery. [2022]Erector spinae plane (ESP) block is a recently described interfacial block, and since 2016, studies have shown that it is a safe technique related to the lower risk of neurovascular and pleural injury comparing to epidural or paravertebral blockade. The application of ESP block in abdominal surgery is relatively limited to case reports and small population studies, which is why we believe every new case of its application should be a valuable contribution.
Effect of ultrasound-guided erector spinae plane block on post-surgical pain in patients undergoing nephrectomy: a single-center, randomized, double-blind, controlled trial. [2022]Erector spinae plane (ESP) block is an alternative to neuraxial block for post-surgical pain in nephrectomy patients. However, no clinical trial has directly compared ESP block with a control group.
Comparison of the efficacy of erector spinae plane block and peritubal infiltration of levobupivacaine for postoperative analgesia following percutaneous nephrolithotomy. [2022]Erector spinae plane (ESP) block is a simple and safe interfascial plane block reported to provide good analgesia after thoracolumbar surgeries. We compared its efficacy with conventional peritubal local anesthetic infiltration following percutaneous nephrolithotomy (PCNL).
Fluoroscopic-guided erector spinae plane block for spine surgery. [2022]Erector spinae plane block (ESPB) is an ultrasound-guided block that can be also done under fluoroscopic guidance, which is usually used to manage postoperative pain of the thoracic and abdominal regions. We describe a successful Fluoroscopic-guided lumbar erector spinae plane block for lower back spinal surgery.
The Erector Spinae Plane Block as Novel Therapy for Renal Colic: A Case Series. [2022]We present a 10-patient case series supporting the use of the erector spinae plane block (ESPB) as a novel approach for the treatment of acute pain from renal colic. An in-plane needle approach was used with either transverse or longitudinal orientation of the ultrasound probe on the affected side, in either seated or prone patient position. These cases showed significant improvement in patient reported pain; suggesting that the ESPB can be used safely and effectively for either primary or adjunctive treatment of acute pain due to renal colic in the emergency department.
The safety and efficacy of ultrasound-guided erector spinae plane block in postoperative analgesic of PCNL: A systematic review and meta-analysis. [2023]The patients received percutaneous nephrolithotomy (PCNL) with severe postoperative pain and discomfort. The erector spinae plane block (ESPB), as a new anesthesia method of plane block, has a positive effect on postoperative analgesia. But evidence of ESPB in PCNL is still lacking. The objective of this study was to systematically analyze the postoperative analgesic effect of ESPB in patients receiving PCNL.