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Toothpaste with curcumin for Bad Breath

N/A
Waitlist Available
Led By Antonio Moretti, DDS, MS
Research Sponsored by University of North Carolina, Chapel Hill
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 21
Awards & highlights

Study Summary

This trial will compare the short-term clinical effect of curcumin-containing toothpaste on halitosis to placebo and will assess any potential shifts in the composition of dental biofilm associated with the use of curcumin-containing toothpaste.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 21
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 21 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Repeated Measures Regression of Volatile Sulphur Compounds (VSC)
Volatile Sulphur Compounds (VSC) at day 14
Volatile Sulphur Compounds (VSC) at day 21
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Toothpaste Containing CurcuminExperimental Treatment1 Intervention
After screening, participants will be randomly assigned to receive toothpaste that contains 0.5% curcumin.
Group II: Toothpaste Without CurcuminPlacebo Group1 Intervention
After screening, participants will be randomly assigned to receive toothpaste that does not contain curcumin.

Find a Location

Who is running the clinical trial?

University of North Carolina, Chapel HillLead Sponsor
1,520 Previous Clinical Trials
4,196,550 Total Patients Enrolled
Colgate PalmoliveIndustry Sponsor
91 Previous Clinical Trials
17,834 Total Patients Enrolled
Antonio Moretti, DDS, MSPrincipal InvestigatorUniversity of North Carolina, Chapel Hill
1 Previous Clinical Trials
50 Total Patients Enrolled
~10 spots leftby Jun 2025
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