Pranayama for Hypertension in Pregnancy
Recruiting in Palo Alto (17 mi)
+1 other location
Overseen byShilpa Babbar, MD
Age: 18+
Sex: Female
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: Children's Mercy Hospital Kansas City
Disqualifiers: Unstable maternal condition, Severe pulmonary disease, others
No Placebo Group
Trial Summary
What is the purpose of this trial?Slow deep breathing actives the vagal nerve and leads to a natural reduction in physiological parameters such as blood pressure, heart rate and digestion. The effects of these techniques have not been assessed in pregnancy. The primary objective is to assess the effects of various yogic deep breathing techniques on blood pressure during pregnancy. The breathing exercises will include Alternate nostril breathing, Bhramari breathing, and Sheetali breathing. A secondary objective will be to assess the effects of these breathing exercises on other physiological parameters including heart rate, heart rate variability, body temperature, cardiac output, vascular resistance and respiratory rate.
Do I need to stop my current medications for this trial?
The trial does not specify if you need to stop taking your current medications. It mentions that participants can have hypertension with or without using antihypertensive medications, so it seems you may continue your current medications.
What data supports the effectiveness of this treatment for hypertension in pregnancy?
Research shows that various breathing exercises, like alternate nostril breathing and Bhramari pranayama, can lower blood pressure in people with hypertension. These exercises help calm the body and may be beneficial for managing high blood pressure during pregnancy.
12345Is pranayama safe for humans?
Research on various pranayama techniques, such as alternate nostril breathing and Bhramari pranayama, suggests they are generally safe for humans, as they have been shown to reduce blood pressure and heart rate without adverse effects.
12467How does the treatment of Pranayama breathing techniques differ from other treatments for hypertension in pregnancy?
Pranayama breathing techniques, such as Alternate Nostril Breathing and Bhramari Breathing, offer a unique approach by focusing on controlled breathing exercises to manage hypertension (high blood pressure) in pregnancy, unlike other treatments that may involve physical exercises like walking or stretching. These techniques are non-invasive and can be practiced anywhere, providing a natural way to potentially reduce stress and improve blood pressure without medication.
89101112Eligibility Criteria
This trial is for English-speaking pregnant women over 18 years old in their third trimester with high blood pressure, either gestational hypertension or chronic hypertension without severe features. It's not for those needing urgent delivery, with pre-eclampsia concerns, severe lung disease, deviated nasal septum, difficulty breathing through the nose, or very low blood pressure.Inclusion Criteria
For Phase II only: You have had consistently high blood pressure before or during the early stages of pregnancy, and may or may not be taking medication for it.
I am a pregnant woman in my third trimester, over 18, and speak English.
I have high blood pressure during pregnancy without organ damage.
+1 more
Exclusion Criteria
I have trouble breathing through my nose.
I have a deviated septum.
I have an ongoing or recent lung condition.
+6 more
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
2-4 weeks
Phase I
Normotensive pregnant women engage in a 15-minute deep breathing technique session with monitoring
1 visit
1 visit (in-person)
Phase II
Hypertensive pregnant women engage in a 15-minute deep breathing technique session with monitoring
1 visit
1 visit (in-person)
Follow-up
Participants are monitored for safety and effectiveness after the intervention
1-2 weeks
Participant Groups
The study tests how Alternate Nostril Breathing, Bhramari Breathing, and Sheetali Breathing affect blood pressure during pregnancy. It also looks at other physiological parameters like heart rate and respiratory rate to see if these yogic techniques can naturally reduce them.
6Treatment groups
Active Control
Group I: Sheetali Breathing Phase IIActive Control1 Intervention
Sheetali breathing for hypertensive women in 3rd trimester of pregnancy
Group II: Sheetali Breathing Phase IActive Control1 Intervention
Sheetali breathing for normotensive women in 3rd trimester of pregnancy
Group III: Alternate Nostril Breathing Phase IIActive Control1 Intervention
Alternate nostril breathing for hypertensive women in 3rd trimester of pregnancy
Group IV: Alternate Nostril Breathing Phase IActive Control1 Intervention
Alternate nostril breathing for normotensive women in 3rd trimester of pregnancy
Group V: Bhramari Breathing Phase IActive Control1 Intervention
Bhramari breathing for normotensive women in 3rd trimester of pregnancy
Group VI: Bhramari Breathing Phase IIActive Control1 Intervention
Bhramari breathing for hypertensive women in 3rd trimester of pregnancy
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Advent Health Birth CenterMerriam, KS
Advent Health Shawnee Mission Birth CenterMerriam, KS
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Who Is Running the Clinical Trial?
Children's Mercy Hospital Kansas CityLead Sponsor
References
Blood pressure and Purdue pegboard scores in individuals with hypertension after alternate nostril breathing, breath awareness, and no intervention. [2021]Previously alternate nostril yoga breathing (anuloma-viloma pranayama) was shown to reduce the blood pressure (BP) in people with hypertension. An elevated BP has been associated with poor performance in certain tasks requiring attention and co-ordination. The Purdue pegboard task assesses manual dexterity and eye-hand co-ordination.
Effect of Sheetali pranayama on cardiac autonomic function among patients with primary hypertension - A randomized controlled trial. [2020]Sheetali pranayama is a cooling pranayama practiced for hypertension (HTN). The effects of Sheetali pranayama, as a solitary intervention on cardiovascular and autonomic changes in hypertension is unknown.
The hypotensive effect of Yoga's breathing exercises: A systematic review. [2018]The aim of this review was to evaluate the effect of pranayama (Yoga's breathing exercises) on BP and its applicability in the treatment of hypertension. Thirteen trials, assessing acute (eight studies) and chronic (five studies) BP response to pranayama were included. Significant BP reductions after pranayama were found in both acute (2-10 mmHg mean SBP reduction, N = 5 studies; 1 mmHg mean DBP reduction, N = 1 study) and chronic studies (4-21 mmHg mean SBP reduction, N = 3 studies; 4-7 mmHg mean DBP reduction, N = 2 studies). The pranayama's effect on BP were not robust against selection bias due to the low quality of studies. But, the lowering BP effect of pranayama is encouraging. The pranayama with slower rhythms and manipulation of the nostrils, mainly with breaths by the left, present better results when compared with the other types and should be the main pranayama applied when the goal is to reduce blood pressure especially in hypertensive patients.
Immediate effect of a slow pace breathing exercise Bhramari pranayama on blood pressure and heart rate. [2022]The study was carried out to evaluate the immediate effect Bhramari pranayama, a slow breathing exercise for 5 minutes on heart rate and blood pressure. Heart rate and blood pressure of volunteers were recorded. The subject was directed to inhale slowly up to the maximum for about 5 seconds and then to exhale slowly up to the maximum for about 15 sec keeping two thumbs on two external auditory canal, index and middle finger together on two closed eyes and ring finger on the two sides of the nose. During exhalation the subject must chant the word "O-U-Mmmma" with a humming nasal sound mimicking the sound of a humming wasp, so that the laryngeal walls and the inner walls of the nostril mildly vibrate (Bhramari pranayama, respiratory rate 3/min). After 5 minutes of this exercise, the blood pressure and heart rate were recorded again. Both the systolic and diastolic blood pressure were found to be'decreased with a slight fall in heart rate. Fall of diastolic pressure and mean pressure were significant. The result indicated that slow pace Bhramari pranayama for 5 minutes, induced parasympathetic dominance on cardiovascular system.
Immediate cardiovascular effects of pranava pranayama in hypertensive patients. [2022]Slow, deep, pranayama-based breathing training has been shown to be effective in reducing blood pressure (BP). The present study was undertaken to determine immediate effects of performing pranava pranayama on cardiovascular parameters in hypertensive patients. 29 hypertensive patients who were on medical treatment and also attending yoga sessions were recruited for the present study. Supine heart rate (HR) and BP were recorded before and after performance of pranava pranayama for five minutes. Post intervention statistical analysis revealed a significant (P
Immediate effect of chandra nadi pranayama (left unilateral forced nostril breathing) on cardiovascular parameters in hypertensive patients. [2022]Recent studies have reported differential physiological and psychological effects produced by exclusive right and left nostril breathing and clinical research is required to prove immediate and sustained efficacy of these techniques in various psychosomatic conditions such as hypertension (HT). The present study was designed to determine immediate effects of 27 rounds of exclusive left nostril breathing, a yogic pranayama technique known as chandra nadi pranayama (CNP) on cardiovascular parameters in patients of essential HT.
Immediate autonomic changes during right nostril breathing and left nostril breathing in regular yoga practitioners. [2022]The ancient Indian science of Yoga makes use of voluntary regulation of breathing to make respiration rhythmic and calm the mind. This practice is called pranayama. Nadisuddhi pranayama means "purification of subtle energy paths," inhalation and exhalation are through alternative nostrils for successive respiratory cycles. Surya Anuloma-Viloma pranayama means "heat generating breathing particle" when the respiratory cycle of inhalation and exhalation is completed through the right nostril exclusively. When completed through the left nostril alone, the practice is called "Chandra Anuloma-Viloma pranayama," which means a heat-dissipating or cooling liberating practice. We compared the effect of right nostril breathing (RNA) and left nostril breathing (LNB) pranayama on heart rate variability.
Pre-eclampsia and nasal CPAP: part 2. Hypertension during pregnancy, chronic snoring, and early nasal CPAP intervention. [2022]To evaluate the potential benefit of nasal continuous positive airway pressure (CPAP) administration in pregnant women recognized to have hypertension early in pregnancy.
The effect of stretching exercise and walking on changes of blood pressure in nulliparous women. [2020]Hypertension in pregnancy is one of the prevalent disorder resulting in maternal death. The aim of this study was to investigate the effect of stretching exercise and walking on changes of blood pressure in nulliparous women during pregnancy.
Plasma nitric oxide levels in pregnant patients with preeclampsia and essential hypertension. [2022]Nitric oxide (NO) production may be an important causal factor in hypertensive disorders during pregnancy. The plasma concentrations of NO2-(+) NO3-, stable metabolites of NO, were measured in 70 nonpregnant women, 323 normotensive pregnant women, 23 pregnant patients with preeclampsia, and 7 pregnant patients with essential hypertension. The normotensive women had higher plasma concentrations (30.0 +/- 0.6 mumol/l) than nonpregnant women (18.3 +/- 1.0 mumol/l; p
The effects of progressive muscular relaxation and breathing control technique on blood pressure during pregnancy. [2020]Hypertensive disorders in pregnancy are the main cause of maternal and fetal mortality; however, they have no definite effective treatment. The researchers aimed to study the effects of progressive muscular relaxation and breathing control technique on blood pressure (BP) during pregnancy.
The effect of walking on pregnancy blood pressure disorders in women susceptible to pregnancy hypertension: A randomized clinical trial. [2020]Hypertension in pregnancy is one of the most important unsolved problems in midwifery, and since it is the main cause of maternal death, preventive intervention measures are essential to control this serious complication. This study aimed to determine the effect of walking on gestational hypertension disorders in women prone to hypertension.