Holistic Treatment for Injection-Related Infections
(IRIS Trial)

Recruiting in Palo Alto (17 mi)

+1 other location

Age: Any Age

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: McMaster University

No Placebo Group

Trial Summary

What is the purpose of this trial?

People who inject drugs are at risk of injection-related infections, like abscesses or infective endocarditis. The Injection-Related InfectionS (IRIS) program hopes to improve treatment for participants by providing a low-barrier, one-stop shop model for people who inject drugs who experience injection-related infections to access more holistic and compassionate care. IRIS is a non-randomized clinical trial, meaning that it offers a specific program to eligible patients. This program offers care for substance use and infectious disease with additional peer support and systems navigation, if interested. The investigators anticipate enrolling 80 participants in the intervention and will follow participants throughout the infection treatment period (estimated 6-12 weeks). The investigators will collect information at the time of enrolment, at the 6-month mark, and monthly via electronic medical chart review. The investigators will use an interrupted time series analysis to evaluate the impact of the intervention on rates of treatment completion, emergency department visits, hospitalizations, and death, before versus after the intervention.

Research Team

Eligibility Criteria

The IRIS program is for individuals in Hamilton, Ontario who use injection drugs and have an infection related to this, like abscesses or heart valve infections. Participants must be 16 or older and able to give informed consent.

Inclusion Criteria

Able to provide informed consent

I have or might have an infection from an injection, including skin, bone, heart infections, Hepatitis C, or HIV.

I am 16 years old or older.

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Treatment Details

Interventions

IRIS Program (Behavioural Intervention)

Trial OverviewThis trial tests a holistic care approach for people with drug-related infections. It provides substance use treatment, infectious disease care, peer support, and help navigating the system without randomizing participants.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Intervention groupExperimental Treatment1 Intervention

Participants in the IRIS program will be offered a one-stop, low-barrier combined care model to address their injection-related infections. Specific program components include: (1) Diagnosis and treatment of injection-related infections; (2) Substance use treatment (3) Peer support; and (4) Care coordination/systems navigation.