~105 spots leftby Apr 2026

Discontinuation of Antiretroviral Therapy in Patients With Asymptomatic HIV Infection

Recruiting in Palo Alto (17 mi)
+33 other locations
Age: Any Age
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine whether patients who have asymptomatic HIV infection can discontinue antiretroviral therapy (ART) without adverse clinical, virologic, or immunologic consequences. This study will also assess the virologic, immunologic, and clinical outcomes in any patients who restart ART.

Research Team

DJ

Daniel J. Skiest, M. D.

Principal Investigator

University of Texas Southwestern Medical Center

Eligibility Criteria

Inclusion Criteria

HIV infection
ART with 2 or more drugs for 6 or more months
CD4+ cell count(s) > 350 cells/mm3 immediately prior to initiation of first ART
See 4 more

Treatment Details

Interventions

  • Antiretroviral Therapy (N/A)

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Wishard HospIndianapolis, IN
The Miriam HospitalProvidence, RI
Comprehensive Care ClinicNashville, TN
Univ of North CarolinaChapel Hill, NC
More Trial Locations
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Who Is Running the Clinical Trial?

National Institute of Allergy and Infectious Diseases (NIAID)

Lead Sponsor

Trials
3361
Patients Recruited
5,516,000+