~23 spots leftby Sep 2026

MuST AKT Program for Kidney Transplant

(MuST AKT Trial)

Recruiting in Palo Alto (17 mi)
Overseen byDr. Shojai
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of Alberta
No Placebo Group

Trial Summary

What is the purpose of this trial?

For people living with kidney failure, the two active treatment options are dialysis or kidney transplantation. Transplantation is optimal, and especially from a living donor - offering patients longer survival, a better quality of life, and cost savings for the health system when compared to dialysis. However, 20% of patients die on dialysis while waiting for a deceased donor organ. As the rate of kidney failure continues to rise, the gap between demand and supply of the organs for transplantation increases. Compared to other provinces in Canada, the rate of living kidney donor transplantation is lower in Alberta, so it is essential that improvements are made to the process around living kidney donor transplantation, for better patient outcomes and care. Our published evidence-based review on strategies to increase living kidney donation, found that for patients with kidney failure, the intervention with the greatest health impact was personalized support, provided by a multidisciplinary team, to inform and educate the patients' social network. A province-wide survey also confirmed that many patients with kidney failure are unable to find a living kidney donor and also find it difficult to approach potential donors due to lack of skills, supports, and resources. The investigators have developed the Multidisciplinary Support To Access living donor Kidney Transplant (MuST AKT) intervention to support potential kidney transplant recipients find living donors through their social networks, and thereby increase the number of living kidney donor transplants in Alberta. The investigators will test the effectiveness of this intervention.

Eligibility Criteria

This trial is for English-speaking individuals with kidney failure who have completed a 'kidney transplant introduction' module and are eligible for a transplant. It's not open to those who already have a donor, have had previous transplants, need multiple organ transplants, or score low on certain psychosocial or literacy tests.

Inclusion Criteria

Successfully completed 'introduction to kidney transplant' module
English speaking
I am eligible for a kidney transplant.

Exclusion Criteria

Previously received organ transplant
Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) Score >20
Potential Living Kidney Donor identified
See 2 more

Treatment Details

Interventions

  • MuST AKT (Behavioral Intervention)
Trial OverviewThe MuST AKT intervention is being tested to help patients find living kidney donors through their social networks. The goal is to increase the number of living donor kidney transplants in Alberta by providing personalized support from a multidisciplinary team.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment1 Intervention
This arm will receive the MuST AKT intervention, which is a multidisciplinary, tailored person-centered behavioural intervention designed to "help and enable" the potential kidney transplant recipients to achieve what is required to receive a living donor kidney transplantation.
Group II: Usual Care (control)Active Control1 Intervention
In the usual care (control) condition, participants will go through the current standard of care, which is a social worker assessment.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
University of Alberta HospitalEdmonton, Canada
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Who Is Running the Clinical Trial?

University of AlbertaLead Sponsor
Alberta Innovates Health SolutionsCollaborator

References