~6 spots leftby Apr 2026

Cognitive and Physical Training for COPD

Recruiting in Palo Alto (17 mi)
DR
Overseen byDmitry Rozenberg, MD PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: University Health Network, Toronto
No Placebo Group

Trial Summary

What is the purpose of this trial?

Cognitive and physical function impairments are common in patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD). Research has shown that cognitive and physical exercise training may be a beneficial strategy to improve physical and cognitive performance in COPD patients; however, interventions combining physical and cognitive training have not been evaluated in this population. The objectives of this research are i) to evaluate the feasibility of an 8-week home-based cognitive-physical training program in COPD patients; and ii) to derive preliminary estimates on intervention efficacy with cognitive-physical training on dual-task performance, physical function, activities of daily living, and health-related quality of life. Related to our research objectives, we hypothesize that i) it will be feasible to safely recruit COPD patients into a home-based cognitive physical training program with 75% adherence and high satisfaction ratings with the prescribed training; and that ii) the combination of cognitive and physical training will be superior to physical training alone for improving dual-task and cognitive performance, physical function, activities of daily living, and health-related quality of life.

Research Team

DR

Dmitry Rozenberg, MD PhD

Principal Investigator

University Health Network, Toronto

Eligibility Criteria

This trial is for adults over 50 with COPD, which is a lung condition that makes it hard to breathe. They should be able to move on their own and have internet access. It's not for people outside this group or those who can't safely do the exercises.

Inclusion Criteria

I have been diagnosed with COPD and my lung function is between 30-80%.
I can move around on my own safely, with or without help like a cane.
I am 50 years old or older.
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Treatment Details

Interventions

  • Cognitive-Physical Training (Behavioral Intervention)
  • Physical Training (Behavioral Intervention)
Trial OverviewThe study tests an 8-week home program combining brain games and physical exercise to see if it helps improve thinking, moving, daily activities, and life quality in COPD patients compared to just physical exercise.
Participant Groups
2Treatment groups
Experimental Treatment
Group I: Physical Training (PT)Experimental Treatment1 Intervention
Participants in the PT group will perform eight weeks of home-based physical exercise training.
Group II: Cognitive-Physical Training (C-PT)Experimental Treatment2 Interventions
Participants in the C-PT will perform eight weeks of home-based cognitive and physical training.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
University Health NetworkToronto, Canada
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Who Is Running the Clinical Trial?

University Health Network, Toronto

Lead Sponsor

Trials
1555
Patients Recruited
526,000+

Canadian Institutes of Health Research (CIHR)

Collaborator

Trials
1417
Patients Recruited
26,550,000+

Boehringer Ingelheim

Industry Sponsor

Trials
2566
Patients Recruited
16,150,000+