Geriatric Care Optimization for Blood Cancers

Recruiting in Palo Alto (17 mi)

Overseen bySarah Wall, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Ohio State University Comprehensive Cancer Center

No Placebo Group

Trial Summary

What is the purpose of this trial?This clinical trial tests whether a geriatric optimization plan (GO!) works to improve survival in patients over 60 with a hematologic malignancy or bone marrow failure syndrome eligible for allogeneic hematopoietic cell transplant. GO! focuses on creating a tailored and specific plan for each patient to make changes in their daily lives. These may include changes to their diet, sleep, activity, medicines, or even referrals to other providers depending on the patient's needs. Studying survival and quality of life in patients over 60 receiving an allogeneic hematopoietic cell transplant may help identify the effects of treatment.

Eligibility Criteria

This trial is for people over 60 with blood cancers or bone marrow failure who are eligible for a stem cell transplant. They must be able to understand English and commit to the study's full duration. Those with dementia, no transplant planned within 6 months, or a scheduled transplant within 30 days can't join.

Inclusion Criteria

I am eligible for a stem cell transplant due to my blood-related cancer or condition.

I am willing to follow the study's schedule and procedures.

I am 60 years old or older.

+1 more

Exclusion Criteria

I am not eligible for a bone marrow transplant from a donor within the next 6 months.

Inability or unwillingness to give written informed consent

I am scheduled for a stem cell transplant from a donor within the next 30 days.

+1 more

Participant Groups

The OTIS Study tests a geriatric optimization plan (GO!) aimed at improving survival in older adults through personalized lifestyle changes like diet, sleep, activity adjustments, medication reviews, and specialist referrals before their stem cell transplants.

1Treatment groups

Experimental Treatment

Group I: Supportive care (GO!)Experimental Treatment4 Interventions

Patients undergo personalized GO! plan consisting of study visits over 50 minutes at baseline and 6 months after first visit or at the time of hospital admission for bone marrow transplant and over 25 minutes at 3 and 12 months after transplant. Patients complete questionnaires once a month for up to 6 months and wear an accelerometer for up to 6 months.