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Thrive Intervention for Mental Illness (THRIVE-SMI Trial)

N/A
Recruiting
Led By Jacqueline M Brooks Carthon, PhD,RN
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Medicaid insured
Be older than 18 years old
Must not have
Individuals under age 18
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, an average of 18 months
Awards & highlights
No Placebo-Only Group

Summary

This trial is evaluating a clinical pathway called THRIVE at HUP-Cedar. The pathway aims to support Medicaid-insured individuals, including those with serious mental illness, after they leave the hospital. The

Who is the study for?
This trial is for adults with Medicaid insurance in Pennsylvania who have been hospitalized and agree to home care. It's designed to help those, especially with serious mental illness, transition after hospitalization.
What is being tested?
The THRIVE clinical pathway is being tested. It includes a home care nurse visit within 48 hours of discharge and ongoing care coordination for 30 days, aiming to reduce readmissions and emergency visits compared to standard care.
What are the potential side effects?
Since this study focuses on a service intervention rather than medication, traditional side effects are not applicable. However, there may be potential challenges or issues related to the implementation of the new care pathway.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am covered by Medicaid.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am under 18 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, an average of 18 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 18 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Primary Care or Specialist Visit
Rates of Emergency Department Visit
Rates of Readmissions
+1 more
Secondary study objectives
Feasibility, Acceptability, Appropriateness, Workload

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: THRIVE InterventionExperimental Treatment1 Intervention
THRIVE Intervention 1-month intensive post discharge case management and care coordination
Group II: Usual CareActive Control1 Intervention
Discharge to home without intensive post-acute case management or care coordination.

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor
2,084 Previous Clinical Trials
42,726,781 Total Patients Enrolled
3 Trials studying Transition Care
13,206 Patients Enrolled for Transition Care
Agency for Healthcare Research and Quality (AHRQ)FED
408 Previous Clinical Trials
6,793,307 Total Patients Enrolled
2 Trials studying Transition Care
5,960 Patients Enrolled for Transition Care
Jacqueline M Brooks Carthon, PhD,RNPrincipal InvestigatorUniversity of Pennsylvania
~165 spots leftby Feb 2026