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Behavioural Intervention

Active dTMS for Methamphetamine Addiction

N/A
Waitlist Available
Led By Claudia B Padula, PhD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Must be within the age range of 25-75.
* Participants must meet Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) criteria for moderate to severe MUD (≥4 diagnostic symptoms).
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months post-treatment
Awards & highlights

Summary

This study aims to evaluate the efficacy of deep transcranial magnetic stimulation (dTMS) as a treatment for Veterans with a methamphetamine use disorder (MUD).

Who is the study for?
This trial is for veterans struggling with methamphetamine addiction. Participants should be seeking treatment and have no other major health issues that could interfere with the study.
What is being tested?
The study tests deep transcranial magnetic stimulation (dTMS) using an H4 coil. Some participants will receive real dTMS, while others get a sham (fake) treatment to compare outcomes.
What are the potential side effects?
dTMS may cause discomfort at the site of stimulation, headache, lightheadedness, or seizures in very rare cases. Most side effects are mild and temporary.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months post-treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months post-treatment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Insula Function
Percentage of Days Abstinent
Secondary study objectives
Binary Relapse
Other Salience Network Function
Resting-State Salience Network

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Active dTMSExperimental Treatment1 Intervention
Participants will receive 30 active dTMS treatments, administered 3 times per day over 10 consecutive business days. Each treatment visit will last approximately 30 minutes in total.
Group II: Sham dTMSPlacebo Group1 Intervention
Participants will receive 30 sham dTMS sessions, administered 3 times per day over 10 consecutive business days. Each treatment visit will last approximately 30 minutes in total.

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,414 Previous Clinical Trials
17,463,001 Total Patients Enrolled
VA Palo Alto Health Care SystemFED
89 Previous Clinical Trials
56,903 Total Patients Enrolled
Claudia B Padula, PhDPrincipal InvestigatorStanford University
~20 spots leftby Dec 2026
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