Deep TMS for Methamphetamine Addiction

Recruiting in Palo Alto (17 mi)

Overseen byClaudia B Padula, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Stanford University

No Placebo Group

Trial Summary

What is the purpose of this trial?This study aims to evaluate the efficacy of deep transcranial magnetic stimulation (dTMS) as a treatment for Veterans with a methamphetamine use disorder (MUD).

Eligibility Criteria

This trial is for veterans struggling with methamphetamine addiction. Participants should be seeking treatment and have no other major health issues that could interfere with the study.

Inclusion Criteria

Participants must meet DSM-5 criteria for moderate to severe MUD (≥4 diagnostic symptoms)

Participants must be able to obtain a Motor Threshold (MT) during the screening process

I am between 25 and 75 years old.

+4 more

Exclusion Criteria

Severe impediment to vision, hearing and/or hand movement likely to interfere with the ability to follow study protocols

I have not attempted suicide nor planned it in the last 30 days.

I am taking medication that affects seizure risk.

+9 more

Participant Groups

The study tests deep transcranial magnetic stimulation (dTMS) using an H4 coil. Some participants will receive real dTMS, while others get a sham (fake) treatment to compare outcomes.

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Active dTMSExperimental Treatment1 Intervention

Participants will receive 30 active dTMS treatments, administered 3 times per day over 10 consecutive business days. Each treatment visit will last approximately 30 minutes in total.

Group II: Sham dTMSPlacebo Group1 Intervention

Participants will receive 30 sham dTMS sessions, administered 3 times per day over 10 consecutive business days. Each treatment visit will last approximately 30 minutes in total.