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Neuropathic Corneal Pain with Ocular Surface Discomfort for Dry Eye Syndrome (NASA Trial)

N/A
Waitlist Available
Led By Pedram Hamrah, MD
Research Sponsored by Tufts Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 1
Awards & highlights
No Placebo-Only Group

Summary

This study is designed to measure how common nerve abnormalities are within a group of patients who feel discomfort within their eyes.

Eligible Conditions
  • Dry Eye Syndrome
  • Neuropathic Pain

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 1
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
To assess the overlap of neuropathic corneal pain with dry eye disease in patients in diseases that are currently thought to be mutually exclusive.
Eye
To establish the prevalence of subtypes of patients with neuropathic corneal pain or with a neuropathic component of dry eye in patients with ocular surface discomfort.
Secondary study objectives
Dry Eye Syndromes
To assess for subtypes of neuropathic corneal pain differences in in vivo confocal microscopy measures between dry eye disease patients and neuropathic corneal pain patients.
Neuralgia
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: Neuropathic Corneal Pain with Ocular Surface DiscomfortExperimental Treatment5 Interventions
Participants diagnosed with neuropathic corneal pain with ocular surface discomfort
Group II: Neuropathic Corneal Pain with Dry Eye DiseaseExperimental Treatment5 Interventions
Participants diagnosed with dry eye disease and neuropathic corneal pain
Group III: NCP or Dry Eye in patients with ocular surface discomfortExperimental Treatment5 Interventions
Participants diagnosed with neuropathic corneal pain or with a neuropathic component of dry eye in patients with ocular surface discomfort

Find a Location

Who is running the clinical trial?

Tufts Medical CenterLead Sponsor
262 Previous Clinical Trials
263,243 Total Patients Enrolled
Coopervision, Inc.Industry Sponsor
163 Previous Clinical Trials
13,196 Total Patients Enrolled
Bausch & Lomb IncorporatedIndustry Sponsor
257 Previous Clinical Trials
57,230 Total Patients Enrolled
~49 spots leftby Dec 2024
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