Popular Trials
Pre-Exercise Protein for Perimenopause
This trial aims to compare the effects of high-intensity interval training (HIIT) and traditional aerobic exercise on metabolism in overweight or obese women going through perimenopause. The study will also look at how eating protein or carbohydrates before exercise affects these outcomes. The goal is to understand how these exercises and dietary choices can help manage weight and improve metabolic health during perimenopause. High-intensity interval training (HIIT) has been shown to significantly decrease body weight and fat mass, with more pronounced effects in premenopausal women.
mTOR inhibitor
Rapamycin for Perimenopause
This trial is testing whether a small dose of rapamycin can delay ovarian aging in women. Rapamycin has shown potential for preserving ovarian health, but using it for an extended period can have negative effects. The goal is to extend the time women remain fertile and delay menopause. This could reduce health risks and improve quality of life for women as they age.
Hormone Therapy
Estradiol for Perimenopause
This trial studies how estradiol, a form of estrogen, affects blood vessel health in peri-menopausal women. The goal is to see if estradiol can improve the function of cells lining the blood vessels, potentially reducing the risk of cardiovascular disease. Estradiol has been shown to reduce cardiovascular disease by direct and indirect effects on the cardiovascular system, with recent evidence suggesting beneficial actions of its metabolites.
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Frequently Asked Questions
Introduction to perimenopause
What are the top hospitals conducting perimenopause research?
While perimenopause may not receive as much attention as other medical conditions, top hospitals are still actively working to understand and address its challenges. In Santa Monica, Citruslabs is currently leading the way with one active clinical trial focused on perimenopause. Although they have yet to conduct any previous trials in this area, their commitment to researching this crucial stage of a woman's life shows promise for future breakthroughs. Similarly, St. Joseph's Healthcare Hamilton in Canada has also initiated one ongoing perimenopause trial without any prior studies completed. Across the border at the University of Delaware in Newark, researchers are delving into perimenopause with their own active clinical trial while lacking historical data from past experiments. Lastly, the UT Southwestern Medical Center in Dallas joins these efforts with an ongoing study dedicated to understanding and addressing perimenopausal symptoms—all four institutions demonstrating that even a single study can contribute significantly towards improving our understanding and management of this transitional period experienced by many women worldwide.
Which are the best cities for perimenopause clinical trials?
When it comes to perimenopause clinical trials, several cities have emerged as leaders in conducting research and development. Santa Monica, California is currently hosting 1 active trial focusing on interventions like Daily Balance Gummy and others. Hamilton, Ontario has also made strides in this area with 1 ongoing study examining Cognitive Behavioural Therapy and other potential treatments. Additionally, Newark, Delaware offers a promising clinical trial focused on Estradiol (Mylan or Vivelle Dot Patch) alongside other interventions. Finally, Dallas, Texas is actively researching the effects of Pregnenolone and various other approaches for managing perimenopausal symptoms. These cities provide individuals with opportunities to participate in innovative trials that contribute to advancements in perimenopause care.
Which are the top treatments for perimenopause being explored in clinical trials?
In the realm of perimenopause research, clinical trials are shedding light on several promising treatments. Leading the pack is hormone therapy (HT), which has shown great potential in alleviating symptoms associated with perimenopause. Another notable contender is selective estrogen receptor modulators (SERMs). This class of drugs offers a targeted approach to managing hormonal imbalances during this transitional phase. Additionally, researchers are exploring non-hormonal options such as antidepressants and botanical therapies like black cohosh to help women navigate through perimenopausal challenges. With ongoing trials, these treatments hold promise for improving quality of life for women experiencing this natural but often challenging stage of life.
What are the most recent clinical trials for perimenopause?
Recent clinical trials have aimed to address the unique challenges faced by women during perimenopause. One notable trial explored the use of estradiol, specifically in the form of Mylan or Vivelle Dot patches. This phase 4 study assessed the effectiveness and safety of these treatments for managing symptoms associated with perimenopause. Another promising avenue being investigated is pregnenolone, which has undergone phase 1 and phase 2 trials to evaluate its potential benefits in alleviating perimenopausal symptoms. As researchers continue their efforts, these studies provide hope for improved management options tailored to meet the needs of women going through this transitional period.
What perimenopause clinical trials were recently completed?
Recently, several clinical trials focused on perimenopause have completed, shedding light on potential interventions and treatments for this transitional phase in a woman's life. These studies provide valuable insights into managing the symptoms and challenges associated with perimenopause. While specific details vary across trials, their completion serves as an encouraging step forward in understanding this crucial stage of hormonal change and its impact on women's health.