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Weight Loss Maintenance for Obesity (POWERS Trial)

N/A

Recruiting

Led By Susan Roberts, PhD

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up end of weight stabilization following at least 7 percent weight loss vs. 52 weeks after weight stabilization following at least 7 percent weight loss

Awards & highlights

No Placebo-Only Group

Summary

This trial will study how weight loss affects obese adults, with the goal of understanding how to maintain weight loss long-term.

Who is the study for?

Adults aged 25-59 with obesity (BMI: 30-<40 kg/m2) who've been stable in weight for the past 6 months, not pregnant or planning pregnancy within two years, without severe heart conditions, thyroid disease requiring medication, renal disease needing dialysis, liver issues, substance abuse problems, extreme dietary restrictions like veganism or very low carb/fat diets. Participants must have internet access and be able to do ergometry testing.

What is being tested?

The study aims to understand why overweight individuals tend to regain weight after a behavioral weight loss program. It involves an initial evaluation followed by up to a 20-week program aiming for at least a 7% weight reduction from baseline within 37 weeks. Successful participants will then be monitored over one year with clinical exams at four and twelve months post-program.

What are the potential side effects?

This trial does not involve medications; hence there are no direct side effects from interventions like drugs. However, participants may experience general stress related to lifestyle changes required during the behavioral weight loss program.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ end of weight stabilization following at least 7 percent weight loss vs. 52 weeks after weight stabilization following at least 7 percent weight loss

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~end of weight stabilization following at least 7 percent weight loss vs. 52 weeks after weight stabilization following at least 7 percent weight loss

This trial's timeline: 3 weeks for screening, Varies for treatment, and end of weight stabilization following at least 7 percent weight loss vs. 52 weeks after weight stabilization following at least 7 percent weight loss for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Weight change from end of weight stabilization following at least 7 percent weight loss to 52 weeks after weight stabilization following at least 7 percent weight loss