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Brain Imaging for Predicting Obesity Risks

N/A
Waitlist Available
Led By Timothy D Nelson, Ph.D.
Research Sponsored by University of Nebraska Lincoln
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 19 years or older
Be older than 18 years old
Must not have
As of 8/13/21, for individuals who were not in the Preschool Problem Solving Study but are invited to participate in the current study because they lived in Lancaster County for at least part of high school, the maximum age for eligibility is 20 years of age.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 seconds after taste delivery
Awards & highlights
No Placebo-Only Group

Summary

This trial looks at how different factors in childhood can lead to obesity later in life by examining the neural vulnerabilities associated with obesity.

Who is the study for?
This trial is for adults who are at least 19 years old and have either taken part in the Preschool Problem Solving Study or lived in Lancaster County, NE during high school. If not from the study, participants must be no older than 20. Pregnant individuals, those with braces, non-removable piercings, hair extensions, or metal inside their body cannot join.
What is being tested?
The study is looking into how childhood and adolescent experiences influence brain responses related to obesity risk in young adulthood using an fMRI while participants taste milkshakes. It aims to identify individual and environmental factors that might predict these neural vulnerabilities.
What are the potential side effects?
There are generally no side effects associated with undergoing an fMRI scan itself; however, some people may feel uncomfortable lying still in a confined space or may experience anxiety due to the loud noises during scanning.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 19 years old or older.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am 20 or younger and lived in Lancaster County during high school.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 seconds after taste delivery
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 seconds after taste delivery for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Reward region activation

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: fMRIExperimental Treatment1 Intervention
Participants are delivered sips of appetizing tastes (milkshake) and tasteless solution throughout the task while in the MRI scanner.

Find a Location

Who is running the clinical trial?

Gretchen Swanson Center for NutritionOTHER
2 Previous Clinical Trials
667 Total Patients Enrolled
University of UtahOTHER
1,147 Previous Clinical Trials
1,698,859 Total Patients Enrolled
16 Trials studying Obesity
2,453 Patients Enrolled for Obesity
Wayne State UniversityOTHER
315 Previous Clinical Trials
110,716 Total Patients Enrolled
4 Trials studying Obesity
628 Patients Enrolled for Obesity
University of Nebraska LincolnLead Sponsor
37 Previous Clinical Trials
12,669 Total Patients Enrolled
2 Trials studying Obesity
80 Patients Enrolled for Obesity
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,464 Previous Clinical Trials
4,337,232 Total Patients Enrolled
472 Trials studying Obesity
590,793 Patients Enrolled for Obesity
University of NebraskaOTHER
555 Previous Clinical Trials
1,145,165 Total Patients Enrolled
10 Trials studying Obesity
3,150 Patients Enrolled for Obesity
The University of Texas at San AntonioOTHER
23 Previous Clinical Trials
7,333 Total Patients Enrolled
4 Trials studying Obesity
1,315 Patients Enrolled for Obesity
Stanford UniversityOTHER
2,491 Previous Clinical Trials
17,517,943 Total Patients Enrolled
72 Trials studying Obesity
270,814 Patients Enrolled for Obesity
Timothy D Nelson, Ph.D.Principal InvestigatorUniversity of Nebraska Lincoln

Media Library

Milkshake fMRI Clinical Trial Eligibility Overview. Trial Name: NCT04522947 — N/A
Obesity Research Study Groups: fMRI
Obesity Clinical Trial 2023: Milkshake fMRI Highlights & Side Effects. Trial Name: NCT04522947 — N/A
Milkshake fMRI 2023 Treatment Timeline for Medical Study. Trial Name: NCT04522947 — N/A
Obesity Patient Testimony for trial: Trial Name: NCT04522947 — N/A
~13 spots leftby Apr 2025
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