Speed Manipulated Adaptive Rehabilitation Therapy Bike for Parkinson's Disease
(SMART Trial)

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: Kent State University

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial uses high-speed cycling on a stationary bike to help people with Parkinson's disease improve their movement. Participants will have personalized bike settings to maximize benefits based on their performance. High-speed cycling on a stationary bike has been shown to improve motor functions in patients with Parkinson's disease, similar to high-intensity rehabilitation programs.

Eligibility Criteria

This trial is for individuals aged 50-79 with idiopathic Parkinson's disease who can safely exercise without the risk of cardiovascular or pulmonary complications. It aims to help those looking to improve their motor function and quality of life through a specialized cycling program.

Inclusion Criteria

I have been diagnosed with Parkinson's disease.

No contraindications to exercise including cardiovascular disease or stroke

I am between 50 and 79 years old.

Exclusion Criteria

I have major heart or lung disease symptoms.

Participant Groups

The study tests dynamic high-cadence cycling, which means pedaling at a speed faster than one's natural pace, to see if it improves movement and functional performance in Parkinson's patients. Participants will cycle in 12 sessions over a month while being monitored for improvements.

2Treatment groups

Experimental Treatment

Active Control

Group I: Adaptive dynamic cyclingExperimental Treatment1 Intervention

For the patient-specific adaptive dynamic cycling group, the optimization process will be done after the 3rd, 6th, and 9th sessions. The optimization procedure is based on sample entropy of cadence calculation from the previous session's cycling performance. After optimization, participants will receive specific settings for the next session.

Group II: Non-adaptive dynamic cyclingActive Control1 Intervention

For the non-adaptive group, individuals will cycle on the dynamic bike with pre-determined settings that will stay constant throughout the exercise protocol.