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Device

DBS Stimulation Patterns for Parkinson's Disease

N/A

Recruiting

Led By Aviva Abosch, MD, PhD

Research Sponsored by University of Nebraska

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Significant stimulation-induced side effects

Not willing to participate in the study

Timeline

Screening 3 weeks

Treatment Varies

Follow Up years 1-2

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing whether different stimulation patterns may be more efficient and effective in treating Parkinson's disease, with fewer side effects.

Who is the study for?

This trial is for Parkinson's Disease patients who have already had a specific brain stimulation device (Medtronic Percept PC) implanted and are responding well to treatment. They must consent to participate, have detectable brain signal patterns, be at least 3 months post-surgery, and optimized on their current therapy.

What is being tested?

The study tests new stimulation patterns from the Medtronic Percept PC DBS device against standard ones in treating Parkinson's. It aims to see if these novel patterns can improve symptoms more effectively with fewer side effects.

What are the potential side effects?

While not explicitly listed, potential side effects may include those typically associated with DBS adjustments such as speech problems, balance issues, tingling sensations or muscle contractions.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I experience severe side effects from my treatment.

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I am not willing to participate in the study.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ years 1-2

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~years 1-2

This trial's timeline: 3 weeks for screening, Varies for treatment, and years 1-2 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Safety and Tolerability of novel DBS stimulation patterns.

Secondary study objectives

Response to novel DBS stimulation patterns.

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: PD with DBSExperimental Treatment1 Intervention

Patients with Parkinson's Disease who were implanted with Medtronic Percept PC for DBS and consent to participate in the study.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of NebraskaLead Sponsor

555 Previous Clinical Trials

1,145,374 Total Patients Enrolled

Aviva Abosch, MD, PhD2.76 ReviewsPrincipal Investigator - University of Nebraska

University of Nebraska

3 Previous Clinical Trials

101 Total Patients Enrolled

5Patient Review

My lobectomy was handled with great care by Dr. Abosch and her team. I was in the hospital for 21 days, and they made sure to keep me and my husband informed and comfortable every step of the way. I'm still curious to know what they learn from my temporal lobe, but I'm grateful for the excellent care I received. We always recommend the University of Colorado to others looking for great doctors.