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Dexmedetomidine for Dexmedetomidine

N/A
Recruiting
Research Sponsored by Ciusss de L'Est de l'Île de Montréal
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from pacu admission to discharge
Awards & highlights

Study Summary

This trial aims to reduce sevoflurane's environmental impact while maintaining its benefits in surgery. An alternative drug, dexmedetomidine, will be tested in a randomized controlled trial.

Eligible Conditions
  • Dexmedetomidine
  • Inhalation Anesthesia
  • Sevoflurane
  • Laparoscopy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from pacu admission to discharge
This trial's timeline: 3 weeks for screening, Varies for treatment, and from pacu admission to discharge for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Sevoflurane
Secondary outcome measures
Vasoconstrictor Agents
Mean end tidal sevoflurane (in %) and MAC needed to maintain the BIS index (Medtronic, Canada) between 40 and 60
Pain
+7 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: DexmedetomidineActive Control1 Intervention
Dexmedetomidine 0.6 mcg/kg (adjusted body weight) ; Administered via infusion pump (Smith Medical Medfusion® 4000 Syringe Infusion Pump) so that the full dose is delivered over 10 minutes during induction of general anesthesia
Group II: PlaceboPlacebo Group1 Intervention
Normal saline in volume equivalent of dexmedetomidine dose according to patient weight ; Administered via infusion pump (Smith Medical Medfusion® 4000 Syringe Infusion Pump) so that the full dose is delivered over 10 minutes during induction of general anesthesia

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Who is running the clinical trial?

Ciusss de L'Est de l'Île de MontréalLead Sponsor
71 Previous Clinical Trials
5,477 Total Patients Enrolled
~35 spots leftby Jun 2025
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