Collagen Protein for Muscle Recovery

Recruiting in Palo Alto (17 mi)

Age: 18 - 65

Sex: Male

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Central Florida

Trial Summary

What is the purpose of this trial?

This study is focused on exploring the gap in the literature by comparing the effects of collagen protein versus placebo supplementation on the musculotendinous unit following muscle damaging protocol. Thus, the purpose of this study is to identify and compare the effect of collagen protein versus placebo supplementation on indirect markers of musculotendinous unit recovery following eccentric calf exercises.

Eligibility Criteria

This trial is for healthy males aged 18-30 who regularly engage in resistance training. They must not have allergies to bovine collagen or maltodextrin, and should pass health questionnaires (PAR-Q+ and HHQ) without any 'yes' responses indicating potential health issues.

Inclusion Criteria

Determined to be healthy by PAR-Q+ and the HHQ

I am a male aged between 18 and 30.

Exclusion Criteria

Untrained (no resistance training in the past 3 months)

Allergy to bovine collagen or maltodextrin

Any response of 'yes' on the PAR-Q+; exclusion criteria noted on the HHQ

Treatment Details

Interventions

Collagen Protein (Protein Supplement)

Trial OverviewThe study compares the effects of collagen protein with a placebo (maltodextrin) on muscle recovery after calf exercises that cause muscle damage. It aims to see if collagen helps muscles and tendons recover better than a non-active substance.

Participant Groups

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: CollagenExperimental Treatment1 Intervention

Collagen supplementation group will have 12 participants. They will perform various physical assessments that include pain scale, pain pressure threshold assessment, body composition, calf circumference measurements, muscle thickness measurements, Achilles tendon length and thickness measurements, myotonography of the calf, isometric force assessments during standing and seated plantarflexion positions, a heel raise test, and a standardized exercise routine focused on eccentric movements, targeting a leg chosen at random. Additionally, they will consume a daily dose of two 30-g amount of collagen peptides derived from bovine hide (commercially available as Vital Proteins or Peptan).

Group II: ControlActive Control1 Intervention

Control group (n=12) will receive no supplement. Control group participants will do all the assessments that the intervention participants are performing, except for the standardized exercise routine focused on the eccentric movements. Randomization will be performed via www.randomizer.org website.

Group III: PlaceboPlacebo Group1 Intervention

Placebo supplementation group will have 12 participants. They will perform various physical assessments that include pain scale, pain pressure threshold assessment, body composition, calf circumference measurements, muscle thickness measurements, Achilles tendon length and thickness measurements, myotonography of the calf, isometric force assessments during standing and seated plantarflexion positions, a heel raise test, and a standardized exercise routine focused on eccentric movements, targeting a leg chosen at random. Additionally, they will consume a daily dose of placebo (two 30 g of pure maltodextrin with no amino acids) mixed in 300 ml of orange Gatorade zero.