Non-Invasive Neuromodulation for Spinal Cord Injury
(RISES-T2 Trial)

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Thomas Jefferson University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The objectives of this study are to (1) determine the effects of neuromodulation techniques on mobility in persons with chronic SCI, as measured by subjective and objective measures, and (2) to determine the optimal combination of techniques that modify mobility and movement in an individual. The neuromodulation techniques explored will be methods of electromagnetic stimulation - that is, electrical stimulation and magnetic stimulation.

Eligibility Criteria

This trial is for individuals with chronic spinal cord injury or disease, at least a year post-injury, who can engage in therapy and have caregiver support. They must be able to consent and participate in recorded sessions. Those with severe medical conditions, uncontrolled symptoms, skin issues where electrodes attach, active implants like pacemakers, or are pregnant/breastfeeding cannot join.

Inclusion Criteria

My spinal injury is classified between A and D on the ASIA scale.

I can take part in physical and occupational therapy programs.

Is willing to undergo audio-visual recording sessions

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Exclusion Criteria

Is not a candidate for other reason determined by the investigators

I do not have any severe health issues that could affect the study.

I have skin damage where electrodes would be placed.

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Treatment Details

Interventions

RISES-T System (Electromagnetic Stimulation)

Trial OverviewThe RISES-T System is being tested to see how non-invasive electrical and magnetic neuromodulation techniques affect mobility in people with chronic spinal injuries. The study aims to find the best combination of these techniques to improve movement.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Experimental Treatment ArmExperimental Treatment1 Intervention

Participants will receive closed-loop transcutaneous spinal cord stimulation via the RISES-T System while completing repetitive task practice