Depression Clinical Trials in Baltimore, MD

Depression Clinical Trials in Baltimore, MD

View the best 10 depression medical studies in Baltimore, Maryland. Access promising new therapies by applying to a Baltimore-based Depression clinical trial.

Trials in Baltimore, Maryland

Here are the top 10 medical studies for depression in Baltimore, Maryland

Michael Bask Gill, B Sc preview

Michael Bask Gill, B Sc

Last Reviewed: March 25th, 2025

Image of Clinical Site in Anaheim, United States.

Lumateperone

Behavioural Intervention

Recruiting1 awardPhase 3
"This trial is studying the effectiveness of a new treatment for children with bipolar disorder who are also experiencing major depressive episodes. The study is being conducted at multiple locations and will involve random assignment of participants to receive
Image of University of Maryland School of Medicine in Baltimore, United States.

Aerobic exercise +1 More

Behavioural Intervention

Recruiting1 awardPhase 2
This trial tests a treatment combining duloxetine and aerobic exercise for adults with knee osteoarthritis and depression. Duloxetine helps manage pain and mood, making it easier for patients to stick to their exercise routine. Duloxetine, an anti-depressant medication, has been recently approved for managing knee osteoarthritis and has shown effectiveness in reducing pain and improving function in patients with osteoarthritis.
Image of University of Maryland Baltimore in Baltimore, United States.

Engagement Navigator Service

Behavioural Intervention

Recruiting1 award1 criteria
This trial will create a new support service to help people and families who are at high risk of not staying engaged in their care. They will involve participants, families, and staff in developing the service,
Image of Johns Hopkins Hospital / Johns Hopkins University in Baltimore, United States.

Transcranial Direct Current Stimulation

Device

Recruiting0 awards
This trial is studying whether a non-invasive brain stimulation technique can help improve non-motor symptoms in people with Parkinson's disease.
Image of Site 4082 in Oceanside, United States.

ALTO-203

Procedure

Recruiting0 awardsPhase 2
This trial aims to study the effects of ALTO-203 in patients with Major Depressive Disorder (MDD) through two treatment periods. In the first period, participants will receive a single dose of
Image of Advanced Research Center /ID# 227073 in Anaheim, United States.

Placebo +1 More

Pharmacotherapy

Recruiting1 awardPhase 3
This trial is testing the safety and effectiveness of Cariprazine for treating depressive episodes in children and teenagers with bipolar I disorder. The goal is to find out if Cariprazine can help young people with this condition. Cariprazine is an atypical antipsychotic recently approved for the treatment of depressive episodes in adults with bipolar I disorder.
Image of Sheppard Pratt Health System in Baltimore, United States.

Psilocybin

Psychedelic

Recruiting1 awardPhase 3
This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.
Image of Johns Hopkins University School of Medicine in Baltimore, United States.

Psilocybin +1 More

Psychedelic Therapy

Recruiting1 awardPhase 1
This trial aims to understand how psilocybin affects chronic pain in patients with chronic low back pain and depression. Participants will receive either a high dose of psilocybin or methylphenidate
Image of Chicago Research Center in Chicago, United States.

Aticaprant

Recruiting1 awardPhase 3
This trial aims to see if aticaprant is effective in preventing the return of depression symptoms when added to antidepressant therapy in individuals with major depressive disorder who have already responded well to aticaprant treatment
Image of For additional information regarding sites, contact 844-687-8522 in Austin, United States.

Placebo +1 More

Recruiting0 awardsPhase 2
This trial is testing a drug to treat Major Depressive Disorder in adults who haven't responded to other treatments. It will last 6 weeks and have 336 subjects in the United States.

Popular Filters

Age 65+
Phase 3
< 50 mile distance
No Placebo

Phase 3 Trials

Chicago, Illinois

Aticaprant + Antidepressant for Depression

Recruiting1 awardPhase 3
Towson, Maryland
This trial aims to see if aticaprant is effective in preventing the return of depression symptoms when added to antidepressant therapy in individuals with major depressive disorder who have already responded well to aticaprant treatment
Anaheim, California

Behavioural Intervention

Lumateperone for Pediatric Bipolar Depression

Recruiting1 awardPhase 3
Baltimore, Maryland
"This trial is studying the effectiveness of a new treatment for children with bipolar disorder who are also experiencing major depressive episodes. The study is being conducted at multiple locations and will involve random assignment of participants to receive
Encino, California

Behavioural Intervention

Solriamfetol for Depression

Recruiting1 awardPhase 3
Media, Pennsylvania
This trial is testing solriamfetol, a medication that may help improve symptoms of depression. It targets adults with major depressive disorder (MDD) who do not have psychotic features. Solriamfetol works by affecting brain chemicals involved in mood regulation, potentially helping to improve mood and reduce depression symptoms.
Baltimore, Maryland

Psychedelic

Psilocybin for Treatment-Resistant Depression

Recruiting1 awardPhase 3
Pikesville, Maryland
This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.
Anaheim, California

Pharmacotherapy

Cariprazine for Bipolar Disorder in Youth

Recruiting1 awardPhase 3
Baltimore, Maryland
This trial is testing the safety and effectiveness of Cariprazine for treating depressive episodes in children and teenagers with bipolar I disorder. The goal is to find out if Cariprazine can help young people with this condition. Cariprazine is an atypical antipsychotic recently approved for the treatment of depressive episodes in adults with bipolar I disorder.
Pico Rivera, California

Lumateperone for Major Depressive Disorder

Recruiting1 awardPhase 3
Philadelphia, Pennsylvania
This trial is testing lumateperone, a medication that may help people with depression who haven't improved with other treatments. The study includes patients diagnosed with Major Depressive Disorder who haven't responded well to their current antidepressants. Lumateperone works by balancing brain chemicals that affect mood, potentially improving depressive symptoms.

Trials With No Placebo

Baltimore, Maryland

Psychedelic Therapy

Psilocybin for Chronic Lower Back Pain and Depression

Recruiting1 awardPhase 1
Baltimore, Maryland
This trial aims to understand how psilocybin affects chronic pain in patients with chronic low back pain and depression. Participants will receive either a high dose of psilocybin or methylphenidate
Philadelphia, Pennsylvania

Behavioural Intervention

TMS for Depression

Recruiting1 award
Philadelphia, Pennsylvania
This trial aims to study how the brain responds to transcranial magnetic stimulation (TMS) in people with depression by focusing on a specific brain region called the subgenual anterior cingulate cortex
Bethesda, Maryland

[18F]PF-06445974 PET Imaging for Depression

Recruiting1 awardPhase 1
Bethesda, Maryland
This trial studies changes in an enzyme in the brain to see if it's lower in people with major depressive disorder during major depressive episodes.
Bethesda, Maryland

Brain Imaging + Ketamine for Suicide Risk

Recruiting1 awardPhase 2
Bethesda, Maryland
This trial is studying what happens in the brain when people have thought about or attempted suicide. It will help researchers develop better treatments for suicidal people.
Baltimore, Maryland

Behavioural Intervention

Engagement Navigator Service for Depression

Recruiting1 award1 criteria
Baltimore, Maryland
This trial will create a new support service to help people and families who are at high risk of not staying engaged in their care. They will involve participants, families, and staff in developing the service,
Washington, District of Columbia

Behavioral Intervention

Group Therapy for Psychosocial Issues

Recruiting1 award
Washington, District of Columbia
"This trial is looking for parents or legal guardians of children with a rare condition to participate in a group program called Rare Group Problem Management Plus. The program aims to help adults with practical and emotional problems related

View More Related Trials

rTMS

Active Closed Loop Real Time fMRI Neurofeedback

Ketamine

Pramipexole ER +1 More

Enhanced Brief Interpersonal Psychotherapy

AXS-05

Care Coordination after Preterm Birth (CCAPB)

Mindfulness-based treatment for insomnia (MBTI) +1 More

Placebo +1 More

Social Media-Based Parenting Program

Psilocybin

TMS+SST +2 More

SMILEY

GET ActivE

Elomia

Taking Action

CYB003

Personalized Daily Text Messages with Financial Incentives +1 More

NMRA-335140 +1 More

NMRA-335140

Mothers and Babies Virtual Group Intervention

Placebo

Healing @ Home Program (H@H 2.0)

ABX-002

NG-nitro-L-arginine methyl ester (L-NAME)

Lurasidone +3 More

NBI-1070770

CRISOL Mente

Trauma Resilience and Recovery Program

Transcranial Electric Stimulation Therapy (TEST)

Aerobic exercise +1 More

Fluoxetine

CAPABLE Transplant

Progressive Muscle Relaxation +1 More

Subanesthetic dose intravenous ketamine (KET) +1 More

Building a Strong Identity and Coping Skills

Mindful Self-Compassion

Adapted Cognitive-Behavioral Therapy +1 More

Placebo +1 More

Behavioral Activation - Rehabilitation

Behavior Activation

Virtual Navigator Program

Psilocybin

Omnis Salutis

Problem-Solving Therapy

Nature Only +1 More

Intermittent Theta Burst Stimulation

Psilocybin

Remote Internet-based Cognitive Behavior Therapy (eCBT)

Transcranial Direct Current Stimulation

BPL-003

OT-led Exercise Group

iCHART +1 More

Mecamylamine

Transcranial Magnetic Stimulation

ENCODE

View more depression clinical trials baltimore

See more medical studies focusing on depression baltimore

Frequently Asked Questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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