SGLT2 Inhibitor
Canagliflozin for Diabetic Kidney Disease
This trial is testing Canagliflozin, a medication that helps remove sugar from the body through urine, on adults with Type 2 diabetes and early kidney disease. The goal is to see if it can protect their kidney function by lowering blood sugar levels.
NAD+ precursor
NAD Augmentation for Diabetic Kidney Disease
This trial is testing whether NMN, a compound that may improve cell function, can help older adults with type 2 diabetes and high urine protein levels. The goal is to see if NMN can reduce kidney damage by improving cell energy production. Participants will receive NMN to compare the effects.
Dietary Supplement
Plant-Focused Diet for Diabetes and Chronic Kidney Disease
"This trial will involve 120 patients with diabetes and kidney disease who will be randomly assigned to follow a plant-focused diet or a standard kidney disease diet for 6 months. The goal is to see if
Popular Filters
Trials for DKD Patients
SGLT2 Inhibitor
Sotagliflozin for Diabetic Kidney Disease
This trial aims to test the effects of a new drug called SOTA on kidney function in people with type 1 diabetes and moderate to advanced kidney disease. Previous studies have shown that SOTA can increase
Glucagon-like peptide-1 (GLP-1) receptor agonist
Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
"This trial aims to see how semaglutide affects kidney function and oxygen levels in people with type 1 diabetes. It will also look at how semaglutide impacts blood sugar levels and safety
Behavioural Intervention
Basic Needs Navigation for Diabetic Kidney Disease
This trial will test a basic needs navigation intervention to see if it can help low-income African Americans with diabetic kidney disease who are experiencing multidimensional adversity. The study will look at feasibility, clinical outcomes, self-care behaviors, and quality of life.
Fibrate
Fenofibrate for Type 1 Diabetes
This trial is to test whether the generic drug fenofibrate can prevent kidney damage in people with type 1 diabetes. 40 participants will be enrolled and given either fenofibrate or placebo for 18 months. Kidney function will be measured at the beginning and end of the study.
Mesenchymal Stem Cell Therapy
Stem Cell Therapy for Chronic Kidney Disease
This trial is testing if using donor stem cells is safe and tolerable for people with chronic kidney disease. The stem cells might help repair their damaged kidneys. Stem cell therapy has shown potential in treating kidney diseases and aiding in kidney regeneration.
Trials for Diabetic Nephropathy Patients
SGLT2 Inhibitor
Sotagliflozin for Diabetic Kidney Disease
This trial aims to test the effects of a new drug called SOTA on kidney function in people with type 1 diabetes and moderate to advanced kidney disease. Previous studies have shown that SOTA can increase
Behavioural Intervention
Basic Needs Navigation for Diabetic Kidney Disease
This trial will test a basic needs navigation intervention to see if it can help low-income African Americans with diabetic kidney disease who are experiencing multidimensional adversity. The study will look at feasibility, clinical outcomes, self-care behaviors, and quality of life.
Fibrate
Fenofibrate for Type 1 Diabetes
This trial is to test whether the generic drug fenofibrate can prevent kidney damage in people with type 1 diabetes. 40 participants will be enrolled and given either fenofibrate or placebo for 18 months. Kidney function will be measured at the beginning and end of the study.
Mesenchymal Stem Cell Therapy
Stem Cell Therapy for Chronic Kidney Disease
This trial is testing if using donor stem cells is safe and tolerable for people with chronic kidney disease. The stem cells might help repair their damaged kidneys. Stem cell therapy has shown potential in treating kidney diseases and aiding in kidney regeneration.
Behavioural Intervention
Exercise Program for Chronic Kidney Disease
This trial is studying how well a combined resistance training and aerobic exercise program works compared to a health education program in improving physical function in people with kidney dysfunction.
Trials With No Placebo
SGLT2 Inhibitor
Combo Diabetes Drug for Type 2 Diabetes
This trial is designed to compare rates of the total number of cardiovascular, kidney, and death events among three alternative treatments for patients with type 2 diabetes (T2D) and either established atherosclerotic cardiovascular disease (ASCVD) or at high risk for ASCVD.
Behavioural Intervention
Basic Needs Navigation for Diabetic Kidney Disease
This trial will test a basic needs navigation intervention to see if it can help low-income African Americans with diabetic kidney disease who are experiencing multidimensional adversity. The study will look at feasibility, clinical outcomes, self-care behaviors, and quality of life.
Mesenchymal Stem Cell Therapy
Stem Cell Therapy for Chronic Kidney Disease
This trial is testing if using donor stem cells is safe and tolerable for people with chronic kidney disease. The stem cells might help repair their damaged kidneys. Stem cell therapy has shown potential in treating kidney diseases and aiding in kidney regeneration.
Endothelin Receptor Antagonist
Atrasentan for Kidney Disease
This trial is testing a pill called atrasentan that may help people with certain kidney diseases by reducing harmful protein levels in their urine. It targets patients whose kidney function is getting worse despite standard treatments. The goal is to see if this medication can protect their kidneys.
Behavioural Intervention
Exercise Program for Chronic Kidney Disease
This trial is studying how well a combined resistance training and aerobic exercise program works compared to a health education program in improving physical function in people with kidney dysfunction.
Genetic Test for Cardiorenal Complications in Type 2 Diabetes
"This trial aims to see if a genetic risk prediction test can help patients with Type 2 Diabetes avoid heart and kidney complications. Patients will be monitored over 18 months to see if knowing their risk helps
Frequently Asked Questions
Introduction to diabetic kidney disease
What are the top hospitals conducting diabetic kidney disease research?
When it comes to advancing the treatment options for diabetic kidney disease, several top hospitals are leading the way. In Winston-Salem, Brookview Hills Research Associates, LLC is actively conducting two clinical trials focused on this condition. With a total of four trials dedicated to diabetic kidney disease since their first recorded trial in 2012, they have been making significant strides in understanding and combating this complex ailment. Moving across the country to Milwaukee, the Medical College of Wisconsin is also heavily involved in this area of research. They currently have two ongoing trials targeting diabetic kidney disease and have made substantial contributions with three completed studies thus far since initiating their first trial in 2022.
In Lawrenceville, Georgia Nephrology Research Institute has emerged as another key player in advancing our knowledge and treatments for diabetic kidney disease. Their commitment is evident through their participation in two active clinical trials focusing on this condition and three completed trials since recording their first study back in 2018.
Meanwhile, Brigham and Women's Hospital located in Boston has dedicated its resources to combatting diabetic kidney disease with two ongoing clinical trials that aim to improve outcomes for patients suffering from this debilitating condition. Since launching their initial trial alongside Brookview Hills Research Associates LLC back in 2012 or simultaneously as other institutions like California Institute of Renal Research situated at Chula Vista; which despite having comparatively lower numbers boasts an impressive count of five previously conducted investigations aiming towards alleviating complications related specifically due to kidneys associated with diabetes
These esteemed hospitals serve as beacons of hope for individuals affected by diabetic kidney disease while highlighting significant medical advancements happening throughout the United States. By working tirelessly on pioneering research initiatives aimed at better understanding and treating this devastating complication of diabetes, these institutions provide much-needed optimism for both current patients and future generations alike
Which are the best cities for diabetic kidney disease clinical trials?
Houston, Texas; Boston, Massachusetts; Aurora, Colorado; Lawrenceville, Georgia; and San Antonio, Texas are the top cities for diabetic kidney disease clinical trials. These cities offer a range of active trials investigating various treatment options such as INV-202 25 mg, Subcutaneous Bremelanotide, Atrasentan, canagliflozin, Fenofibrate, Pentoxifylline, Clinical Investigation and Renin-Angiotensin (RAAS) blockers in combination with Spironolactone among others. With their significant research efforts and multiple ongoing studies focused on combating diabetic kidney disease specifically these cities provide valuable opportunities for participating in cutting-edge clinical trials aiming to improve patient outcomes.
Which are the top treatments for diabetic kidney disease being explored in clinical trials?
Clinical trials exploring treatments for diabetic kidney disease have highlighted several promising options. Fenofibrate, an established medication, is currently undergoing one active trial and has been involved in a total of three clinical trials focused on diabetic kidney disease since its introduction in 2016. Another notable treatment under investigation is allogeneic adipose-derived mesenchymal stem cells (MSC) with a single infusion, which is being studied in one ongoing trial and was first listed as a potential therapy in 2021. Additionally, atrasentan is generating interest with one active trial and four past trials dedicated to diabetic kidney disease after being introduced back in 2011. These innovative approaches hold the possibility of transforming the landscape of treatment options for individuals suffering from this debilitating condition.
What are the most recent clinical trials for diabetic kidney disease?
Recent clinical trials have provided promising prospects for individuals with diabetic kidney disease, offering potential breakthroughs in treatment. Among these trials is the Renal Autologous Cell Therapy (REACT), a Phase 1 study aiming to utilize autologous cells as a therapeutic approach for diabetic kidney disease. Additionally, the Investigational Product - MIB 626 has exhibited encouraging results in its Phase 2 trial as a potential treatment option. Another notable trial examined the effectiveness of Subcutaneous Bremelanotide, showcasing its promise in mitigating the impact of diabetic kidney disease. Furthermore, INV-202 and canagliflozin have also shown positive outcomes during their respective Phase 2 studies. These recent advancements bring hope and optimism for improving the lives of those affected by this condition.
What diabetic kidney disease clinical trials were recently completed?
Several clinical trials investigating potential treatments for diabetic kidney disease have recently concluded, bringing hope to individuals affected by this condition. In April 2021, Boehringer Ingelheim successfully completed a trial evaluating the effectiveness of BI 685509. Similarly, CSL Behring wrapped up their study on CSL346 in September 2020. Furthermore, AstraZeneca completed a trial focusing on MEDI3506 in November 2019. These milestones signify significant progress in the pursuit of improved therapies for diabetic kidney disease and offer promise for patients dealing with its impact.