Beta3-Adrenergic Receptor Agonist
Mirabegron + B Complex Plus Vitamin C for Brown Adipose Tissue
This trial tests if the drug mirabegron can increase brown fat activity in people aged 18-40 with different body types. The drug helps brown fat burn more energy, which might aid in weight loss and better sugar management.
Hormone Therapy
Kisspeptin for Polycystic Ovary Syndrome
This trial involves giving kisspeptin and another hormone to people with PCOS to see how it affects their hormone levels. The goal is to understand if kisspeptin can help regulate their reproductive hormones. Kisspeptin has recently emerged as a key regulator of the reproductive system in women and has been shown to stimulate the secretion of another important hormone.
Popular Filters
Trials for PCOS Patients
Dietary Supplement
Fish Oil + Metformin for Polycystic Ovary Syndrome
"This trial aims to see how adding fish oil to the diet of overweight-obese young women with PCOS compares to the standard treatment with metformin in terms of their blood fats and how the body
Biguanides
Metformin vs. Birth Control Pills for Polycystic Ovary Syndrome
This trial will compare metformin to oral combined hormonal contraceptives in treating Polycystic Ovary Syndrome in women of later reproductive age, using the Polycystic Ovary Syndrome Questionnaire score as a proxy for patient satisfaction.
Dietary Supplement
Inositol for Polycystic Ovary Syndrome
This trial tests if inositol, a dietary supplement, can reduce high hormone levels in women with PCOS. It aims to see if inositol can lower testosterone and improve symptoms by balancing hormone levels. Inositol has been shown to improve ovarian function and metabolic profiles in women with PCOS, with myo-inositol (MI) and D-chiro-inositol (DCI) being particularly effective.
Trials for Metabolic Syndrome Patients
Dietary Supplement
Inositol for Polycystic Ovary Syndrome
This trial tests if inositol, a dietary supplement, can reduce high hormone levels in women with PCOS. It aims to see if inositol can lower testosterone and improve symptoms by balancing hormone levels. Inositol has been shown to improve ovarian function and metabolic profiles in women with PCOS, with myo-inositol (MI) and D-chiro-inositol (DCI) being particularly effective.
Behavioral Intervention
Weight Loss Program for PCOS and Obesity
This trial aims to see how much weight patients with PCOS can lose in a 24-week intensive weight loss program called STREAM. They also want to see how other health markers like insulin sensitivity will improve
Behavioral Intervention
Lifestyle Interventions for Chronic Disease
This trial aims to address chronic diseases in rural areas by increasing physical activity and healthy body composition, as an effective and affordable treatment with fewer side effects than pharmaceuticals.
Trials With No Placebo
Dietary Supplement
Fish Oil + Metformin for Polycystic Ovary Syndrome
"This trial aims to see how adding fish oil to the diet of overweight-obese young women with PCOS compares to the standard treatment with metformin in terms of their blood fats and how the body
Biguanides
Metformin vs. Birth Control Pills for Polycystic Ovary Syndrome
This trial will compare metformin to oral combined hormonal contraceptives in treating Polycystic Ovary Syndrome in women of later reproductive age, using the Polycystic Ovary Syndrome Questionnaire score as a proxy for patient satisfaction.
Frequently Asked Questions
Introduction to pcos
What are the top hospitals conducting pcos research?
Polycystic ovary syndrome (PCOS) is a complex hormonal disorder affecting millions of women worldwide. In the pursuit of effective treatments and advancements in understanding this condition, several leading hospitals have emerged as frontrunners in conducting clinical trials dedicated to PCOS research. The University of Virginia in Charlottesville, renowned for its expertise in reproductive health, takes top billing with six active PCOS trials and seven historically completed studies. Since their first recorded trial back in 2000, researchers at this esteemed institution have been committed to unraveling the mysteries surrounding PCOS.
Not far behind is Massachusetts General Hospital located in Boston, whose three ongoing PCOS trials demonstrate their commitment to advancing healthcare outcomes for those affected by this disorder. Though they may have fewer historical trials under their belt—three to be exact—the hospital's dedication to exploring innovative solutions shines through since recording their inaugural trial focused on PCOS management just over a decade ago, in 2009.
In addition to these remarkable institutions' contributions towards understanding and treating PCOS, the University of Virginia Center for Research in Reproduction has also made significant strides. With three active clinical trials dedicated specifically to PCOS currently underway and an impressive total of eight previous investigations conducted since initiating their first trial related to this condition back in 2006.
Meanwhile, another arm affiliated with the University of Virginia that deserves recognition is the Center for Research on Reproduction which boasts two ongoing clinical tests targeting PCOS while having contributed significantly through conducting preceding six experiments from starting its pioneering investigation on such cases way back until 2006. And last but not least - making valuable contributions relatively recently- The University of Virginia Clinical Research Unit joins forces with two active pcos clincal projects alongwith previously executed two more; theirs can be traced back only five years ago,in2016.
These notable hospitals situated across Charlottesville and Boston are collectively striving towards conquering polycystic ovary syndrome by pushing the boundaries of medical research and treatment options. Their tireless efforts illuminate a path towards better understanding, improved management, and ultimately enhanced quality of life for women living with PCOS around the globe.
Which are the best cities for pcos clinical trials?
Charlottesville, Virginia; Boston, Massachusetts; San Francisco, California; Chicago, Illinois; and Davenport, Iowa are among the top cities for PCOS clinical trials. In Charlottesville, there are 13 active trials focusing on medications like Metformin, Spironolactone, and Flutamide. Similarly in Boston and San Francisco, researchers are investigating various treatments including kisspeptin, GnRH, Tildacerfont, CPAP groups and vigorous exercise interventions. Meanwhile in Chicago and Davenport studies center around Salsalate use for PCOS management along with other interventions like Letrozole and time-restricted eating (TRE). These cities offer individuals with PCOS access to cutting-edge research aimed at improving treatment options for this common endocrine disorder.
Which are the top treatments for pcos being explored in clinical trials?
Clinical trials are actively exploring potential treatments for polycystic ovary syndrome (PCOS). Metformin, a well-known medication, is currently being tested in four ongoing trials dedicated to PCOS. Since its introduction in 2000, it has been involved in a total of 76 clinical trials related to this condition. Another treatment under investigation is spironolactone, which is being studied in two active PCOS trials and has been listed since 2016. Additionally, flutamide shows promise as a potential therapy with two active PCOS trials and five all-time clinical trials since its first listing in 2006. Continued research into these treatments offers hope for managing the challenging symptoms associated with PCOS.
What are the most recent clinical trials for pcos?
Exciting advancements are being made in the field of polycystic ovary syndrome (PCOS) research, with recent clinical trials shedding light on potential treatment options. One such trial focuses on kisspeptin and GnRH as a means to address PCOS symptoms. Another study explores the effectiveness of tildacerfont in managing the condition. Additionally, letrozole has been investigated for its impact on PCOS patients during Phase 4 trials. Similarly, an ongoing Phase 4 trial is evaluating the use of etonogestrel/ethinyl estradiol vaginal ring in individuals with PCOS. Lastly, promising results have emerged from a Phase 2 trial examining the efficacy of inositol for treating this complex condition. These latest clinical trials offer hope and promise for those affected by PCOS, bringing us closer to improved management strategies and better quality of life for patients.
What pcos clinical trials were recently completed?
Recently completed clinical trials focusing on polycystic ovary syndrome (PCOS) have provided valuable insights into potential treatments for this complex condition. In December 2017, Yale University concluded a trial investigating the use of GnRH antagonists as a therapeutic approach. Meanwhile, in August 2014, researchers at the University of Colorado, Denver completed a trial studying the effectiveness of Byetta 5Mcg Pen Injection. Additionally, in April 2013, the University of California, Los Angeles wrapped up their study on Flutamide's impact on PCOS management. These important studies enhance our understanding and pave the way for future advancements in addressing PCOS-related challenges faced by women worldwide.