Beta3-Adrenergic Receptor Agonist
Mirabegron + B Complex Plus Vitamin C for Brown Adipose Tissue
Recruiting0 awardsPhase 1
Bethesda, Maryland
This trial tests if the drug mirabegron can increase brown fat activity in people aged 18-40 with different body types. The drug helps brown fat burn more energy, which might aid in weight loss and better sugar management.
Hormone Therapy
Kisspeptin for Polycystic Ovary Syndrome
Recruiting1 awardPhase 1
Boston, Massachusetts
This trial involves giving kisspeptin and another hormone to people with PCOS to see how it affects their hormone levels. The goal is to understand if kisspeptin can help regulate their reproductive hormones. Kisspeptin has recently emerged as a key regulator of the reproductive system in women and has been shown to stimulate the secretion of another important hormone.
Popular Filters
Trials for PCOS Patients
Progestin
Hormone Therapy for Polycystic Ovary Syndrome
Recruiting0 awardsPhase < 1
Charlottesville, Virginia
This trial is testing if flutamide, which blocks testosterone, can help women with PCOS improve their hormone regulation. The study aims to see if this medication can enhance the body's response to progesterone. Flutamide has been used to treat high levels of male hormones in women with PCOS, but its use is limited by potential liver damage and cost.
Dietary Supplement
Myo-Inositol + Letrozole for PCOS Infertility
Recruiting0 awards6 criteria
Oklahoma City, Oklahoma
This trial will compare the effect of letrozole with a placebo, versus letrozole with inositols, on pregnancy rates in women undergoing ovulation induction. The trial will be double-blind, meaning that neither the participants nor the research team will know which treatment each person is receiving.
Biguanides
Metformin vs. Birth Control Pills for Polycystic Ovary Syndrome
Recruiting3 awardsPhase < 1
Charlottesville, Virginia
This trial will compare metformin to oral combined hormonal contraceptives in treating Polycystic Ovary Syndrome in women of later reproductive age, using the Polycystic Ovary Syndrome Questionnaire score as a proxy for patient satisfaction.
Dietary Supplement
Inositol for Polycystic Ovary Syndrome
Recruiting0 awardsPhase 2
Hershey, Pennsylvania
This trial tests if inositol, a dietary supplement, can reduce high hormone levels in women with PCOS. It aims to see if inositol can lower testosterone and improve symptoms by balancing hormone levels. Inositol has been shown to improve ovarian function and metabolic profiles in women with PCOS, with myo-inositol (MI) and D-chiro-inositol (DCI) being particularly effective.
Trials for Metabolic Syndrome Patients
Dietary Supplement
Inositol for Polycystic Ovary Syndrome
Recruiting0 awardsPhase 2
Hershey, Pennsylvania
This trial tests if inositol, a dietary supplement, can reduce high hormone levels in women with PCOS. It aims to see if inositol can lower testosterone and improve symptoms by balancing hormone levels. Inositol has been shown to improve ovarian function and metabolic profiles in women with PCOS, with myo-inositol (MI) and D-chiro-inositol (DCI) being particularly effective.
Hormone Therapy
Oral Contraceptives + Resistant Starch for Polycystic Ovary Syndrome
Recruiting0 awardsPhase 2
Philadelphia, Pennsylvania
This trial will include women with PCOS to see if adding resistant starch to their treatment regimen for 12 weeks will improve heart and metabolic health and gut bacteria compared to a placebo.
Behavioral Intervention
Weight Loss Program for PCOS and Obesity
Recruiting1 award
Ottawa, Ontario
This trial aims to see how much weight patients with PCOS can lose in a 24-week intensive weight loss program called STREAM. They also want to see how other health markers like insulin sensitivity will improve
Behavioral Intervention
Lifestyle Interventions for Chronic Disease
Recruiting1 award2 criteria
Lewisburg, West Virginia
This trial aims to address chronic diseases in rural areas by increasing physical activity and healthy body composition, as an effective and affordable treatment with fewer side effects than pharmaceuticals.
Continuous Glucose Monitoring for Polycystic Ovary Syndrome
Recruiting1 award2 criteria
San Francisco, California
This trial uses a wearable device to monitor blood sugar levels in women with PCOS. The goal is to see if continuous monitoring can help manage their blood sugar and improve their overall health. The study will compare results from those using the device to those who do not. These devices were primarily developed for individuals with diabetes but are now being used by people without diabetes for various health applications.
Trials With No Placebo
Biguanides
Metformin vs. Birth Control Pills for Polycystic Ovary Syndrome
Recruiting3 awardsPhase < 1
Charlottesville, Virginia
This trial will compare metformin to oral combined hormonal contraceptives in treating Polycystic Ovary Syndrome in women of later reproductive age, using the Polycystic Ovary Syndrome Questionnaire score as a proxy for patient satisfaction.
Behavioral Intervention
Weight Loss Program for PCOS and Obesity
Recruiting1 award
Ottawa, Ontario
This trial aims to see how much weight patients with PCOS can lose in a 24-week intensive weight loss program called STREAM. They also want to see how other health markers like insulin sensitivity will improve
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.