Griseofulvin

Tinea Pedis, Tinea barbae, Kerion Celsi + 3 more

Treatment

11 FDA approvals

0 Active Studies for Griseofulvin

What is Griseofulvin

Griseofulvin

The Generic name of this drug

Treatment Summary

Griseofulvin is an antibiotic used to treat fungal infections on the skin, scalp, and nails. It is taken orally and can help to clear up tinea infections.

Griseofulvin MICROSIZE

is the brand name

image of different drug pills on a surface

Griseofulvin Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Griseofulvin MICROSIZE

Griseofulvin

1971

41

Approved as Treatment by the FDA

Griseofulvin, otherwise known as Griseofulvin MICROSIZE, is approved by the FDA for 11 uses including Tinea barbae and Tinea Cruris .

Tinea barbae

Tinea Cruris

Tinea Corporis

Tinea Unguium

Tinea Capitis

Tinea Pedis

Tinea Cruris

Kerion Celsi

Onychomycosis

Foot

Tinea

Effectiveness

How Griseofulvin Affects Patients

Griseofulvin is a fungal product used to treat certain types of skin infections caused by fungi. It has been used for over forty years and works by attaching itself to the skin cells affected by the fungus and prevents it from spreading. When the skin cells with the Griseofulvin attached reach the infected area, it binds to the fungus's cells and stops them from multiplying.

How Griseofulvin works in the body

Griseofulvin works by preventing the growth of fungi on the skin. The exact way it does this is not clear, but we think it stops fungal cells from dividing and keeps them from making new acid. It also binds to and disrupts the way fungal cells move and divide, by sticking to the proteins that make up their microtubules. Griseofulvin can also bind to human cells, and then once it's at the fungus site, it binds to their microtubules, changing the way they divide.

When to interrupt dosage

The stipulated dose of Griseofulvin is contingent upon the determined circumstance, for example Tinea cruris, Tinea barbae and Tinea Unguium. The amount of dosage is contingent upon the administration strategy identified in the table below.

Condition

Dosage

Administration

Tinea barbae

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated

Kerion Celsi

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated

Tinea Cruris

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated

Tinea Pedis

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated

Tinea

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated

Onychomycosis

, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg

, Oral, Tablet - Oral, Tablet, Suspension - Oral, Suspension, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated

Warnings

Griseofulvin Contraindications

Condition

Risk Level

Notes

Porphyrias

Do Not Combine

Liver Failure

Do Not Combine

There are 20 known major drug interactions with Griseofulvin.

Common Griseofulvin Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Griseofulvin.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Griseofulvin.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Griseofulvin.

Alpelisib

Major

The metabolism of Alpelisib can be increased when combined with Griseofulvin.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Griseofulvin.

Griseofulvin Toxicity & Overdose Risk

Common side effects of this drug include headaches, stomach issues, and skin rashes.

image of a doctor in a lab doing drug, clinical research

Griseofulvin Novel Uses: Which Conditions Have a Clinical Trial Featuring Griseofulvin?

At present, there are zero active trials assessing the potential of Griseofulvin to provide relief for Tinea Corporis, Tinea barbae and Tinea Pedis.

Condition

Clinical Trials

Trial Phases

Tinea Pedis

0 Actively Recruiting

Tinea barbae

0 Actively Recruiting

Tinea

0 Actively Recruiting

Onychomycosis

0 Actively Recruiting

Tinea Cruris

0 Actively Recruiting

Kerion Celsi

0 Actively Recruiting

Griseofulvin Reviews: What are patients saying about Griseofulvin?

5

Patient Review

11/29/2007

Griseofulvin for Ringworm of Scalp

My son contracted ringworm from school and the doctors prescribed this medication. It is highly effective for treatment of this particular fungal infection. He has been on this medication for 3 days and already they are clearing up.

4.7

Patient Review

12/18/2007

Griseofulvin for Ringworm of Scalp

It took a little while, but this treatment finally got rid of my two year old's ringworm. It was easy enough to give because it came in a flavor that they enjoyed.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about griseofulvin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the most common side effect of griseofulvin?

"You may experience headaches, nausea, vomiting, diarrhea, or general stomach upset. You may also feel tired, dizzy, or have trouble sleeping."

Answered by AI

How long does it take for griseofulvin to work?

"It takes two to four weeks for skin infections and four to six weeks for hair and scalp infections to be completely gone."

Answered by AI

Is griseofulvin better than fluconazole?

"The study found that griseofulvin was only slightly better than fluconazole. Lower doses for both griseofulvin and fluconazole required significantly longer treatment duration to cure the fungus infection, regardless of the type of fungus."

Answered by AI

Is griseofulvin an antibiotic or antifungal?

"Griseofulvin is an antifungal agent that is used to treat superficial tinea infections, fungal infections of the fingernails, and fungal infections of the toes. Griseofulvin is an antibiotic that is given by mouth in the treatment of tinea infections."

Answered by AI