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What is Griseofulvin
GriseofulvinThe Generic name of this drug
Treatment SummaryGriseofulvin is an antibiotic used to treat fungal infections on the skin, scalp, and nails. It is taken orally and can help to clear up tinea infections.
Griseofulvin MICROSIZEis the brand name
Griseofulvin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Griseofulvin MICROSIZE
Griseofulvin
1971
41
Approved as Treatment by the FDA
Griseofulvin, otherwise known as Griseofulvin MICROSIZE, is approved by the FDA for 11 uses including Tinea Pedis and Tinea cruris .Tinea Pedis
Tinea cruris
Kerion Celsi
Onychomycosis
Tinea Unguium
Tinea Capitis
Foot
Tinea barbae
Tinea Cruris
Tinea Corporis
Tinea
Effectiveness
How Griseofulvin Affects PatientsGriseofulvin is a fungal product used to treat certain types of skin infections caused by fungi. It has been used for over forty years and works by attaching itself to the skin cells affected by the fungus and prevents it from spreading. When the skin cells with the Griseofulvin attached reach the infected area, it binds to the fungus's cells and stops them from multiplying.
How Griseofulvin works in the bodyGriseofulvin works by preventing the growth of fungi on the skin. The exact way it does this is not clear, but we think it stops fungal cells from dividing and keeps them from making new acid. It also binds to and disrupts the way fungal cells move and divide, by sticking to the proteins that make up their microtubules. Griseofulvin can also bind to human cells, and then once it's at the fungus site, it binds to their microtubules, changing the way they divide.
When to interrupt dosage
The stipulated dose of Griseofulvin is contingent upon the determined circumstance, for example Tinea cruris, Tinea barbae and Tinea Unguium. The amount of dosage is contingent upon the administration strategy identified in the table below.Condition
Dosage
Administration
Tinea barbae
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Kerion Celsi
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea cruris
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea Pedis
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Tinea
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Onychomycosis
, 250.0 mg, 500.0 mg, 125.0 mg/mL, 125.0 mg, 330.0 mg
, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
Griseofulvin ContraindicationsCondition
Risk Level
Notes
Porphyrias
Do Not Combine
Liver Failure
Do Not Combine
Common Griseofulvin Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Griseofulvin.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Griseofulvin.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Griseofulvin.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Griseofulvin.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Griseofulvin.
Griseofulvin Toxicity & Overdose RiskCommon side effects of this drug include headaches, stomach issues, and skin rashes.
Griseofulvin Novel Uses: Which Conditions Have a Clinical Trial Featuring Griseofulvin?
At present, there are zero active trials assessing the potential of Griseofulvin to provide relief for Tinea Corporis, Tinea barbae and Tinea Pedis.Condition
Clinical Trials
Trial Phases
Tinea Pedis
0 Actively Recruiting
Tinea barbae
0 Actively Recruiting
Tinea
0 Actively Recruiting
Onychomycosis
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
Kerion Celsi
0 Actively Recruiting
Griseofulvin Reviews: What are patients saying about Griseofulvin?
5Patient Review
11/29/2007 My son contracted ringworm from school and the doctors prescribed this medication. It is highly effective for treatment of this particular fungal infection. He has been on this medication for 3 days and already they are clearing up.
4.7Patient Review
12/18/2007 It took a little while, but this treatment finally got rid of my two year old's ringworm. It was easy enough to give because it came in a flavor that they enjoyed.
Patient Q&A Section about griseofulvin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the most common side effect of griseofulvin?
"You may experience headaches, nausea, vomiting, diarrhea, or general stomach upset. You may also feel tired, dizzy, or have trouble sleeping."
Answered by AI
How long does it take for griseofulvin to work?
"It takes two to four weeks for skin infections and four to six weeks for hair and scalp infections to be completely gone."
Answered by AI
Is griseofulvin better than fluconazole?
"The study found that griseofulvin was only slightly better than fluconazole. Lower doses for both griseofulvin and fluconazole required significantly longer treatment duration to cure the fungus infection, regardless of the type of fungus."
Answered by AI
Is griseofulvin an antibiotic or antifungal?
"Griseofulvin is an antifungal agent that is used to treat superficial tinea infections, fungal infections of the fingernails, and fungal infections of the toes. Griseofulvin is an antibiotic that is given by mouth in the treatment of tinea infections."
Answered by AI