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What is Lexiscan
RegadenosonThe Generic name of this drug
Treatment SummaryRegadenoson is a medication used to widen the arteries of the heart in order to improve blood flow and assist with myocardial perfusion imagining. It works by activating a certain type of adenosine receptor in the body. Regadenoson was approved by the FDA in 2008 and is manufactured by Astellas.
Lexiscanis the brand name
Lexiscan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lexiscan
Regadenoson
2008
10
Effectiveness
How Lexiscan Affects PatientsRegadenoson increases the amount of blood flowing to the heart, and this effect is usually seen within 30 seconds. The increased blood flow lasts for around 10 minutes. The drug works better in areas with normal coronary arteries, as blocked arteries will take up less of the drug and produce a weaker signal.
How Lexiscan works in the bodyRegadenoson is a drug that helps to open up the blood vessels, increasing the flow of blood to your heart. It is designed to mimic the effects of adenosine, which naturally relaxes the blood vessels. Regadenoson is being tested to help diagnose medical conditions, and has been found to help restore normal heart rhythm in patients with certain heart conditions. It works by targeting the A2A receptor, which helps to slow down the conduction time through the A-V node and interrupts reentry pathways.
When to interrupt dosage
The measure of Lexiscan is contingent upon the diagnosed condition. The dosage likewise differs as per the delivery technique (e.g. Injection, solution or Injection - Intravenous) reflected in the table below.Condition
Dosage
Administration
radionuclide myocardial perfusion imaging
0.08 mg/mL, , 0.4 mg
, Intravenous, Injection, solution, Injection, solution - Intravenous
Warnings
Lexiscan ContraindicationsCondition
Risk Level
Notes
Sinus Node Dysfunction
Do Not Combine
second or third degree AV block
Do Not Combine
Common Lexiscan Drug Interactions
Drug Name
Risk Level
Description
Lexiscan Toxicity & Overdose RiskCommon side effects of regadenoson include shortness of breath, headache, redness of the skin, chest discomfort, dizziness, chest pain, and nausea. The maximum safe dose for males in a supine position is 20 µg/kg, and 10 µg/kg in a standing position.
Lexiscan Novel Uses: Which Conditions Have a Clinical Trial Featuring Lexiscan?
At present, there are zero studies assessing the potential of Lexiscan for radionuclide myocardial perfusion imaging.Condition
Clinical Trials
Trial Phases
radionuclide myocardial perfusion imaging
0 Actively Recruiting
Lexiscan Reviews: What are patients saying about Lexiscan?
5Patient Review
11/10/2022 I had no issues whatsoever when taking this medicine as part of a nuclear stress test. The shortness of breath I experienced lasted less than five minutes and wasn't severe at all.
3Patient Review
4/9/2022 I'm scheduled to have a LEXI soon, and I'm really scared. I've been having shortness of breath for two years now, and recently started having gastro issues as well. It feels like heart failure, but after multiple trips to the doctor, we still don't have any answers. If you're reading this, be grateful that you're not in my position.
3Patient Review
6/15/2020 I wasn't sure what to expect going in, but I definitely felt the effects of the drug almost immediately. It was a very strange sensation-I suddenly felt like I had just run a marathon or something. I was a bit breathless, lightheaded, and then it passed. It's not pleasant by any means, but it's also not terrible. And it doesn't last long at all-it's been maybe an hour since I had it done and I'm already starting to feel better.
2.3Patient Review
12/4/2020 Still feeling really terrible even after taking the reversal agent. I'm experiencing chest pain, coughing, weakness, shaking, fatigue, poor concentration, and rapid heart beat. Contacted my doctor but still waiting to hear back about if this is normal or not.
1Patient Review
3/6/2022 This was the most horrible experience of my life. I had a pulmonary embolism in 2017, and the LexiScan was 10 times worse on the pain scale! I'm still traumatized from this procedure.
1Patient Review
10/4/2020 Immediately after being injected, I found it difficult to breathe. The nurse practitioner said this was normal, but as a doctor myself, I know that this is not the case. I had to lay down for the duration of the imaging process, which was uncomfortable. There were few side effects with Persantine otherwise.
1Patient Review
11/1/2022 I had a very serious reaction to this injection. I flatlined for 20 seconds and 10 minutes after the injection, I had to have chest compressions. This drug is dangerous and should not be used lightly.
Patient Q&A Section about lexiscan
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of Lexiscan?
"You may experience a headache, dizziness, nausea, stomach discomfort, decreased sense of taste, mild chest discomfort, shortness of breath, or a flushing (warmth, redness, or tingly feeling) under your skin."
Answered by AI
Is a Lexiscan the same as a stress test?
"An Adenosine or Lexiscan nuclear scan is a test where Adenosine or Lexiscan is used to stress the heart, similar to the exercise nuclear stress test. Adenosine is infused over 4-6 minutes, while Lexiscan is given over a few seconds."
Answered by AI
What does a Lexiscan test for?
"A LEXI stress test uses nuclear medicine to create pictures of your heart while you are at rest and during stress.
A Nuclear Sit Down Stress Test, also known as a Lexiscan stress test or LEXI, is designed to evaluate the condition of your coronary arteries. These arteries supply the heart with blood. A LEXI stress test uses nuclear medicine to create pictures of your heart while you are at rest and during stress."
Answered by AI
How is a Lexiscan stress test performed?
"Lexiscan or Adenoscan are administered intravenously to patients who cannot adequately exercise. These drugs dilate the coronary arteries and increase blood flow so that coronary artery obstructions can be identified."
Answered by AI