Lexiscan

radionuclide myocardial perfusion imaging

Treatment

0 Active Studies for Lexiscan

What is Lexiscan

Regadenoson

The Generic name of this drug

Treatment Summary

Regadenoson is a medication used to widen the arteries of the heart in order to improve blood flow and assist with myocardial perfusion imagining. It works by activating a certain type of adenosine receptor in the body. Regadenoson was approved by the FDA in 2008 and is manufactured by Astellas.

Lexiscan

is the brand name

image of different drug pills on a surface

Lexiscan Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Lexiscan

Regadenoson

2008

10

Effectiveness

How Lexiscan Affects Patients

Regadenoson increases the amount of blood flowing to the heart, and this effect is usually seen within 30 seconds. The increased blood flow lasts for around 10 minutes. The drug works better in areas with normal coronary arteries, as blocked arteries will take up less of the drug and produce a weaker signal.

How Lexiscan works in the body

Regadenoson is a drug that helps to open up the blood vessels, increasing the flow of blood to your heart. It is designed to mimic the effects of adenosine, which naturally relaxes the blood vessels. Regadenoson is being tested to help diagnose medical conditions, and has been found to help restore normal heart rhythm in patients with certain heart conditions. It works by targeting the A2A receptor, which helps to slow down the conduction time through the A-V node and interrupts reentry pathways.

When to interrupt dosage

The measure of Lexiscan is contingent upon the diagnosed condition. The dosage likewise differs as per the delivery technique (e.g. Injection, solution or Injection - Intravenous) reflected in the table below.

Condition

Dosage

Administration

radionuclide myocardial perfusion imaging

0.08 mg/mL, , 0.4 mg

Intravenous, Injection, solution - Intravenous, , Injection, solution

Warnings

Lexiscan Contraindications

Condition

Risk Level

Notes

Sick Sinus Syndrome

Do Not Combine

Atrioventricular Block

Do Not Combine

Common Lexiscan Drug Interactions

Drug Name

Risk Level

Description

Lexiscan Toxicity & Overdose Risk

Common side effects of regadenoson include shortness of breath, headache, redness of the skin, chest discomfort, dizziness, chest pain, and nausea. The maximum safe dose for males in a supine position is 20 µg/kg, and 10 µg/kg in a standing position.

image of a doctor in a lab doing drug, clinical research

Lexiscan Novel Uses: Which Conditions Have a Clinical Trial Featuring Lexiscan?

At present, there are zero studies assessing the potential of Lexiscan for radionuclide myocardial perfusion imaging.

Condition

Clinical Trials

Trial Phases

radionuclide myocardial perfusion imaging

0 Actively Recruiting

Lexiscan Reviews: What are patients saying about Lexiscan?

5

Patient Review

11/10/2022

Lexiscan for Medication to Aid Study of the Blood Flow in the Heart

I had no issues whatsoever when taking this medicine as part of a nuclear stress test. The shortness of breath I experienced lasted less than five minutes and wasn't severe at all.

3

Patient Review

4/9/2022

Lexiscan for Medication to Aid Study of the Blood Flow in the Heart

I'm scheduled to have a LEXI soon, and I'm really scared. I've been having shortness of breath for two years now, and recently started having gastro issues as well. It feels like heart failure, but after multiple trips to the doctor, we still don't have any answers. If you're reading this, be grateful that you're not in my position.

3

Patient Review

6/15/2020

Lexiscan for Medication to Aid Study of the Blood Flow in the Heart

I wasn't sure what to expect going in, but I definitely felt the effects of the drug almost immediately. It was a very strange sensation-I suddenly felt like I had just run a marathon or something. I was a bit breathless, lightheaded, and then it passed. It's not pleasant by any means, but it's also not terrible. And it doesn't last long at all-it's been maybe an hour since I had it done and I'm already starting to feel better.

2.3

Patient Review

12/4/2020

Lexiscan for Medication to Aid Study of the Blood Flow in the Heart

Still feeling really terrible even after taking the reversal agent. I'm experiencing chest pain, coughing, weakness, shaking, fatigue, poor concentration, and rapid heart beat. Contacted my doctor but still waiting to hear back about if this is normal or not.

1

Patient Review

3/6/2022

Lexiscan for Medication to Aid Study of the Blood Flow in the Heart

This was the most horrible experience of my life. I had a pulmonary embolism in 2017, and the LexiScan was 10 times worse on the pain scale! I'm still traumatized from this procedure.

1

Patient Review

10/4/2020

Lexiscan for Medication to Aid Study of the Blood Flow in the Heart

Immediately after being injected, I found it difficult to breathe. The nurse practitioner said this was normal, but as a doctor myself, I know that this is not the case. I had to lay down for the duration of the imaging process, which was uncomfortable. There were few side effects with Persantine otherwise.

1

Patient Review

11/1/2022

Lexiscan for Medication to Aid Study of the Blood Flow in the Heart

I had a very serious reaction to this injection. I flatlined for 20 seconds and 10 minutes after the injection, I had to have chest compressions. This drug is dangerous and should not be used lightly.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about lexiscan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of Lexiscan?

"You may experience a headache, dizziness, nausea, stomach discomfort, decreased sense of taste, mild chest discomfort, shortness of breath, or a flushing (warmth, redness, or tingly feeling) under your skin."

Answered by AI

Is a Lexiscan the same as a stress test?

"An Adenosine or Lexiscan nuclear scan is a test where Adenosine or Lexiscan is used to stress the heart, similar to the exercise nuclear stress test. Adenosine is infused over 4-6 minutes, while Lexiscan is given over a few seconds."

Answered by AI

What does a Lexiscan test for?

"A LEXI stress test uses nuclear medicine to create pictures of your heart while you are at rest and during stress.

A Nuclear Sit Down Stress Test, also known as a Lexiscan stress test or LEXI, is designed to evaluate the condition of your coronary arteries. These arteries supply the heart with blood. A LEXI stress test uses nuclear medicine to create pictures of your heart while you are at rest and during stress."

Answered by AI

How is a Lexiscan stress test performed?

"Lexiscan or Adenoscan are administered intravenously to patients who cannot adequately exercise. These drugs dilate the coronary arteries and increase blood flow so that coronary artery obstructions can be identified."

Answered by AI