Morphabond Er

Chronic Pain, Pain, Therapeutic procedure

Treatment

3 FDA approvals

0 Active Studies for Morphabond Er

Treatment for

Chronic Pain

What is Morphabond Er

Morphine

The Generic name of this drug

Treatment Summary

Morphine is a strong pain reliever, first extracted from poppy plants in 1805. It is still used today to treat severe pain, however other medications such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone are often used as alternatives due to the risks associated with morphine use (tolerance, withdrawal, and abuse). Morphine was officially approved by the FDA in 1941.

Morphine Sulfate

is the brand name

image of different drug pills on a surface

Morphabond Er Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Morphine Sulfate

Morphine

1971

459

Approved as Treatment by the FDA

Morphine, also known as Morphine Sulfate, is approved by the FDA for 3 uses including Pain, Chronic and Chronic Pain .

Pain, Chronic

Helps manage Pain, Chronic

Chronic Pain

Helps manage Pain, Chronic

Pain

Effectiveness

How Morphabond Er Affects Patients

Morphine blocks pain signals from reaching the brain, which helps reduce pain. Its effects can take anywhere from 6-30 minutes to kick in. Taking too much morphine and other opioids can cause permanent changes in the brain. Morphine works differently in men and women, with women needing less of it to feel the same effects. Morphine-6-glucuronide is much weaker than morphine when it comes to constricting the pupils.

How Morphabond Er works in the body

Morphine-6-glucuronide is the primary chemical responsible for the effects of morphine. It binds to two types of opioid receptors: mu and kappa. The mu-opioid receptor is responsible for morphine's effects on the brain's reward system, breathing, and addiction. The kappa-opioid receptor helps with pain relief.

When to interrupt dosage

The suggested dosage of Morphabond Er is founded on the diagnosed condition, including Therapeutic procedure, Pain and Chronic Pain. The amount additionally alters as per the method of delivery exemplified in the table below.

Condition

Dosage

Administration

Therapeutic procedure

10.0 mg/mL, , 20.0 mg, 50.0 mg, 60.0 mg, 30.0 mg, 10.0 mg, 80.0 mg, 100.0 mg, 200.0 mg, 0.5 mg/mL, 1.0 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 3.0 mg/mL, 100.0 mg/mL, 5.0 mg, 15.0 mg, 20.0 mg/mL, 15.0 mg/mL, 5.0 mg/mL, 8.0 mg/mL, 4.0 mg/mL, 90.0 mg, 120.0 mg, 40.0 mg, 70.0 mg, 130.0 mg, 150.0 mg, 2.0 mg/mL, 45.0 mg, 75.0 mg, 25.0 mg, 40.0 mg/mL, 1.1 mg/mL, 0.1 mg/mL

Oral, Solution - Oral, Capsule, extended release, Capsule, extended release - Oral, , Injection, solution, Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Injection, solution - Epidural; Intrathecal; Intravenous, Intravenous; Subcutaneous, Injection, solution - Intravenous; Subcutaneous, Solution, Rectal, Suppository - Rectal, Suppository, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, solution - Intravenous, Intrathecal; Intravenous, Epidural; Intramuscular; Intrathecal; Intravenous, Injection, solution - Epidural; Intramuscular; Intrathecal; Intravenous, Capsule, Capsule - Oral, Solution - Epidural; Intravenous; Subcutaneous, Suppository, extended release, Suppository, extended release - Rectal, Syrup, Syrup - Oral, Injection, Injection - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Epidural; Intrathecal; Intravenous, Injection - Epidural; Intrathecal; Intravenous, Epidural; Intrathecal, Injection, solution - Epidural; Intrathecal, Solution, concentrate, Solution, concentrate - Oral, Tincture, Tincture - Oral, Liquid - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Parenteral, Injection - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intrathecal; Intravenous, Solution / drops, Solution / drops - Oral, Epidural, Solution - Epidural, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous, Epidural; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid - Intravenous; Subcutaneous, Solution - Intravenous, Liquid - Intravenous, Intramuscular, Injection - Intramuscular, Tablet, film coated, Tablet, film coated - Oral, Injection, lipid complex, Injection, lipid complex - Epidural, Solution - Parenteral, Injection - Parenteral, Intrathecal, Injection, solution - Intrathecal, Injection - Epidural; Intrathecal, Injection, solution - Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid, Epidural; Intraspinal; Intrathecal; Intravenous; Subarachnoid

Pain

Chronic Pain

Warnings

Morphabond Er has six contraindications, so it must not be simultaneously taken with any of the conditions in the table below.

Morphabond Er Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Morphine may interact with Pulse Frequency

Pulse Frequency

Do Not Combine

Mental Depression

Do Not Combine

Asthma

Do Not Combine

Gastrointestinal obstruction

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Morphabond Er.

Common Morphabond Er Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Morphine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Morphine.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Morphine.

Eluxadoline

Major

The risk or severity of constipation can be increased when Morphine is combined with Eluxadoline.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Morphine.

Morphabond Er Toxicity & Overdose Risk

The toxic dose of this drug is 0.78 micrograms per milliliter for males and 0.98 micrograms per milliliter for females. An overdose can cause difficulty breathing, drowsiness, limp muscles, cold and clammy skin, constricted pupils, and dilated pupils. Severe symptoms may include fluid buildup in the lungs, slow heartbeat, low blood pressure, heart failure, and even death. Treatment of an overdose involves providing oxygen, medications to raise blood pressure, and a medicine called naloxone.

Morphabond Er Novel Uses: Which Conditions Have a Clinical Trial Featuring Morphabond Er?

24 active clinical trials are currently being conducted to assess the potential of Morphabond Er in providing therapeutic intervention, alleviating Pain and ameliorating Chronic Pain.

Condition

Clinical Trials

Trial Phases

Pain

0 Actively Recruiting

Therapeutic procedure

0 Actively Recruiting

Chronic Pain

0 Actively Recruiting

Morphabond Er Reviews: What are patients saying about Morphabond Er?

4.3

Patient Review

11/20/2018

Morphabond Er for Chronic Pain

Though I follow the prescribed dosage, these pills do nothing for me in terms of relief. All they do is make me feel like I'm sweating all the time.

2.3

Patient Review

9/10/2019

Morphabond Er for Chronic Pain

I was pretty disappointed with this treatment. It didn't work nearly as well as my usual, generic brand. I think it releases too slowly over too long of a time compared to the other. I now constantly feel pain and need more medication.

Patient Q&A Section about morphabond er

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can MS Contin 15 mg ER be crushed?

"You should swallow MS Contin tablets whole, and not break, chew, dissolve or crush them."

Answered by AI

Can you crush morphine sulfate immediate release?

"Take morphine sulfate extended-release tablets as a whole. Do not cut, break, chew, crush, dissolve, snort, or inject morphine sulfate extended-release tablets as this can lead to an overdose and death."

Answered by AI

What is MST analgesic?

"MST Continus is a medication used to relieve severe pain over a period of 12 hours. It contains the active ingredient morphine which belongs to a group of medicines called strong analgesics or 'painkillers'."

Answered by AI

What is Morphabond used for?

"Morphabond is a Morphine Sulfate that is used to treat the symptoms of Acute Pain and Chronic Severe Pain. It may be used alone or with other medications."

Answered by AI