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What is Testosterone Enanthate
Testosterone enanthateThe Generic name of this drug
Treatment SummaryTestosterone enanthate is a form of testosterone that is injected into the body and released slowly over time. It was first approved for medical use in 1953 and is now commonly used to treat low testosterone levels. In 2017, 6.5 million prescriptions were filled for testosterone therapy, most of them being injectable or topical forms of the hormone. In 2018, the FDA approved Xyosted, a once-weekly testosterone enanthate product designed to be self-administered with a single dose, disposable autoinjector. This new formulation removes the need for frequent visits to the clinic for injections.
Delatestrylis the brand name
Testosterone Enanthate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Delatestryl
Testosterone enanthate
1953
8
Effectiveness
How Testosterone Enanthate Affects PatientsTaking testosterone enanthate can raise the amount of testosterone in the body up to four times the normal level within 24 hours. After this initial increase, the levels of testosterone stay higher than normal for 3-5 days. Taking testosterone enanthate regularly can suppress levels of dihydrotestosterone, PSA, HDL and FSH, and also slightly raise the level of estradiol in the body. The suppression of dihydrotestosterone and FSH can last up to 14 days after stopping treatment. There is no effect on mood or sexual activity from taking testosterone enanthate.
How Testosterone Enanthate works in the bodyTestosterone affects the body in two ways. It can either bind to the androgen receptor directly, or it can be converted to DHT, which binds more strongly to the receptor. This binding triggers a reaction in the cell nucleus, which affects certain genes and causes physical changes, like hair growth and increased muscle mass. Testosterone is also responsible for the growth and development of male organs and body parts. Low levels of testosterone can lead to male hypogonadism, which is caused either by problems with the gonads or with the hypothalamus or pituitary gland.
When to interrupt dosage
The measure of Testosterone Enanthate is contingent upon the recognized affliction, including Hypogonadism, Hypogonadism and Hypergonadotropic Hypogonadism. The amount additionally deviates as indicated by the technique of delivery (e.g. Liquid - Intramuscular or Injection, solution) specified in the table below.Condition
Dosage
Administration
Hypogonadism
, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Intramuscular, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Solution, Injection, Injection - Intramuscular, Subcutaneous, Injection - Subcutaneous
Hypogonadism
, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Intramuscular, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Solution, Injection, Injection - Intramuscular, Subcutaneous, Injection - Subcutaneous
Hypogonadism
, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Intramuscular, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Solution, Injection, Injection - Intramuscular, Subcutaneous, Injection - Subcutaneous
Warnings
Testosterone Enanthate ContraindicationsCondition
Risk Level
Notes
Hypogonadism
Do Not Combine
Breast Cancer
Do Not Combine
Common Testosterone Enanthate Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Testosterone enanthate.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Testosterone enanthate.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Testosterone enanthate.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Testosterone enanthate.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Testosterone enanthate.
Testosterone Enanthate Toxicity & Overdose RiskTaking testosterone enanthate could increase the risk of blood clots and create more tumors. It is not safe for pregnant women or children and can cause fertility issues in men. Using testosterone enanthate can also cause prostate problems in older adults.
Testosterone Enanthate Novel Uses: Which Conditions Have a Clinical Trial Featuring Testosterone Enanthate?
Presently, 7 trials are assessing the potential of Testosterone Enanthate to provide relief from Hypogonadism, Eunuchoidism and Hypergonadotropic Hypogonadism.Condition
Clinical Trials
Trial Phases
Hypogonadism
0 Actively Recruiting
Hypogonadism
0 Actively Recruiting
Hypogonadism
6 Actively Recruiting
Phase 4, Phase 2, Phase 1, Not Applicable
Testosterone Enanthate Reviews: What are patients saying about Testosterone Enanthate?
5Patient Review
9/19/2009 I was diagnosed with Klienfelters Syndrome about 6 years ago. I tried using the testerone replacement patch and the gel, but saw little effect. However, after two weeks of using the injection, I have seen a big difference in many areas of my daily activities.
5Patient Review
12/22/2008 I'm 45 and using two cc's per week, and I feel incredible! Not only have I maintained my hairline, but my libido is through the roof. I was also taking Ambien CR to help me sleep, but within three weeks of starting this treatment, I was sleeping like a baby without it! Overall, I've just been feeling really good lately.
5Patient Review
11/21/2014 I've been on this treatment for two years and have seen some great results. I've lost 80lbs and my stamina and energy has increased a lot. The only side effect I've experienced is acne, but that's not always the case.
5Patient Review
8/3/2011 I would recommend this treatment to anyone.
4.7Patient Review
2/20/2014 I was diagnosed with low testosterone and given a prescription for 100 mg per week. Prior to the shots, I was very moody, depressed, gaining weight, and really just tired all the time. I had quit working out after over 20 years of regular visits to the gym. 3 years into treatment, I'm now back in the gym and my mood has improved significantly. Additionally, my erectile dysfunction has resolved itself; something that was a big issue for me before starting this medication regimen. All in all, it's worked well for me.
4Patient Review
2/14/2011 I found this treatment to be much better than gels or patches that I've tried in the past. The only downside is that it can cause too much hemoglobin buildup, requiring frequent blood tests.
Patient Q&A Section about testosterone enanthate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can I build muscle with testosterone enanthate?
"Testosterone enanthate has been shown to increase strength within 6-12 weeks of administration, but it is unclear if the benefits are evident in less than 6 weeks."
Answered by AI
What is testosterone enanthate used for?
"Testosterone enanthate is a long-acting form of testosterone, so it lasts for several weeks in the body.
Testosterone enanthate is an injectable form of testosterone used to treat low testosterone in males, as well as breast cancer that has spread to other parts of the body in females. Testosterone enanthate is a long-acting form of testosterone, so it is effective for several weeks."
Answered by AI
What is difference between testosterone cypionate and enanthate?
"The chemical structure of testosterone cypionate and testosterone enanthate are very similar, with the exception of an additional carbon atom in the former that makes its half life slightly longer at 8 days, as opposed to the latter's 7."
Answered by AI