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What is Vigamox
MoxifloxacinThe Generic name of this drug
Treatment SummaryMoxifloxacin is an antibiotic manufactured by Bayer AG. It is used to treat bacterial infections orally, and is sold under the brand name Avelox (or Avalox in some countries).
Aveloxis the brand name
Vigamox Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Avelox
Moxifloxacin
1999
86
Approved as Treatment by the FDA
Moxifloxacin, also known as Avelox, is approved by the FDA for 9 uses including Sinusitis and Sinusitis .Sinusitis
Sinusitis
Skin Infections
Plague
Community Acquired Pneumonia (CAP)
Plague
prophylaxis of Plague
Bronchitis
Communicable Diseases
Effectiveness
How Vigamox Affects PatientsMoxifloxacin is an antibiotic used to treat bacterial infections. It is effective against a variety of bacteria, including Corynebacterium, Staphylococcus, Streptococcus, Acinetobacter, Haemophilus, and Chlamydia. Moxifloxacin works by stopping the bacteria from making copies of its DNA. It binds to an enzyme called DNA gyrase that helps the bacteria replicate, and has 100 times more affinity for bacteria DNA gyrase than it does for mammalian DNA. As a broad-spectrum antibiotic, moxifloxacin is
How Vigamox works in the bodyMoxifloxacin kills bacteria by blocking two enzymes, DNA gyrase and topoisomerase IV. DNA gyrase is important for making copies of bacterial DNA, while topoisomerase IV helps the bacteria divide. Blocking these enzymes prevents the bacteria from reproducing, leading to its death.
When to interrupt dosage
The prescribed measure of Vigamox is contingent upon the diagnosed condition, including ocular bacterial infections, Sinusitis and Skin Infections. The amount is contingent upon the method of delivery (e.g. Solution - Intravenous or Injection, solution - Ophthalmic), as outlined in the table below.Condition
Dosage
Administration
Community Acquired Pneumonia (CAP)
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Postoperative Infections
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
prophylaxis of Plague
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Conjunctivitis, Bacterial
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
ocular bacterial infections
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Bronchitis
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Postoperative Inflammatory Response
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Communicable Diseases
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Plague
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Sinusitis
400.0 mg, , 5.0 mg/mL, 0.5 %, 4.0 mg/mL, 1.0 mg/mL, 0.5 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, Tablet - Oral, Intravenous, Solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops, Solution / drops - Ophthalmic, Injection, suspension, Injection, suspension - Ophthalmic, Injection, solution - Ophthalmic, Suspension, Suspension - Ophthalmic, Intraocular, Injection, solution - Intraocular, Kit, Kit - Ophthalmic
Warnings
There are 20 known major drug interactions with Vigamox.Common Vigamox Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Amiodarone.
Amitriptyline
Major
Moxifloxacin may increase the QTc-prolonging activities of Amitriptyline.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Artemether.
Vigamox Toxicity & Overdose RiskAn overdose of Diphenhydramine could cause decreased activity, drowsiness, tremors, seizures, vomiting, and diarrhea. The lowest amount that would be lethal in mice and rats is 100mg/kg.
Vigamox Novel Uses: Which Conditions Have a Clinical Trial Featuring Vigamox?
24 active clinical trials are presently assessing the potential of Vigamox to provide prophylaxis for Plague, Skin Infections and Bacterial Conjunctivitis.Condition
Clinical Trials
Trial Phases
Postoperative Inflammatory Response
1 Actively Recruiting
Phase 4
Plague
0 Actively Recruiting
Postoperative Infections
0 Actively Recruiting
Communicable Diseases
1 Actively Recruiting
Phase 2
Conjunctivitis, Bacterial
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Sinusitis
4 Actively Recruiting
Not Applicable, Phase 4
prophylaxis of Plague
0 Actively Recruiting
Bronchitis
6 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2
Community Acquired Pneumonia (CAP)
3 Actively Recruiting
Not Applicable, Phase 1, Phase 3
Vigamox Reviews: What are patients saying about Vigamox?
5Patient Review
7/19/2017 We've tried a lot of different treatments for pink eye in our family, and this one is by far the best. It's affordable because our insurance covers it, and it really works wonders.
5Patient Review
1/11/2017 I was really shocked at how much this costs in the US. I paid less than $10 for it in Romania.
4.7Patient Review
3/31/2016 The high cost of this medication is outrageous, especially when compared to other countries where it is a fraction of the price. I'm telling you, somebody is making a killing off of selling this stuff. That said, it was the only thing that helped me after trying several other options.
4.3Patient Review
1/17/2016 Vigamox really helped with my pink eye, but now I have to deal with dry eyes as a result. It's been awhile since the original problem, and my eyes are still quite dry by the end of each day. In the morning, it's especially bad and feels like my eyelids are glued shut. Not ideal, but better than pink eye!
3.7Patient Review
5/18/2016 The price tag on this is pretty hefty, and it's not even a very large bottle. I would recommend seeing if your doctor can give you a different option for pink eye that doesn't break the bank.
Patient Q&A Section about vigamox
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What eye infections does Vigamox treat?
"Moxifloxacin is an antibiotic in the fluoroquinolone family that fights bacteria in the body. It come in the form of an ophthalmic solution for treating bacterial infections of the eyes. However, it will not work on viral or fungal infections of the eye."
Answered by AI
What is Vigamox used to treat?
"Vigamox is an antibiotic used to kill bacteria causing infections in the eyes."
Answered by AI
Is Vigamox eye drops a steroid?
"Are Vigamox and Tobradex effective for treating the same thing?
Yes, Vigamox and Tobradex are both effective for treating bacterial infections of the eyes."
Answered by AI
How many times a day do you use Vigamox?
"For adults, children, and newborns, the typical dosage of Vigamox is 1 drop in the affected eye(s) 3 times a day for 7 days."
Answered by AI