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PRP Therapy for Alopecia After Breast Cancer Treatment

Phase < 1

Waitlist Available

Led By Anthony M Rossi, MD

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Have a clinical diagnosis of endocrine therapy induced alopecia (EIA) for breast cancer:

Ludwig stage 1-3 for women

Must not have

An active scalp dermatologic condition (e.g. alopecia areata, scalp psoriasis), scalp skin cancer (e.g. BCC, SCC), a pre-existing condition with sequelae on the scalp (e.g. scarring alopecia) or acute infection

Actively receiving anticoagulant medication

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks from baseline

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing a treatment for hair loss that involves injecting platelets from a person's own blood into their scalp.

Who is the study for?

This trial is for women over 18 with hair loss after breast cancer treatment, who haven't used endocrine therapy in the last 6 months or certain alopecia treatments without a 3-month break. It's not for those pregnant, breastfeeding, with scalp conditions, past hair transplants, taking anticoagulants (unless stopped a week before), or on fish oil/NSAIDs without pausing them.

What is being tested?

The study tests PRP treatment where participants' own platelets are injected into their scalp to treat hair loss caused by cancer therapy. The process involves blood collection and platelet separation every four weeks for three months.

What are the potential side effects?

Potential side effects may include discomfort at injection sites, bleeding, infection risk at the treated area of the scalp, headache or temporary changes in sensation around the treated areas.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have hair loss due to hormone therapy for breast cancer.

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I am a woman with Ludwig stage 1-3 hair loss.

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I stopped using minoxidil or spironolactone for hair loss 3 months ago.

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I am taking or have taken drugs like tamoxifen for hormone therapy.

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I am taking or have taken aromatase inhibitors.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have an active skin condition on my scalp or a history of scalp skin cancer.

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I am currently taking blood thinner medication.

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I have had or will have radiation therapy to my brain.

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I have a blood disorder affecting clotting or platelets.

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I haven't used any hair loss products in the last 2 weeks.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks from baseline

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks from baseline

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks from baseline for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Hair Density

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Female Breast Cancer PtsExperimental Treatment1 Intervention

Participants include female breast cancer patients who either receive endocrine therapy and suffer from endocrine induced alopecia or suffer from post chemotherapy induced alopecia.

0 / 10Eligibility criteria met