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A Phase 1 Trial to Investigate the Biological Equivalence of 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese Participants

Phase 1
Waitlist Available
Research Sponsored by Idorsia Pharmaceuticals Ltd.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

This trial tests if two different doses of a drug are equally effective in healthy Japanese men & women.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Treatment B (5 × 25 mg daridorexant)Experimental Treatment1 Intervention
Participants will receive a single oral dose of 2 × 25 mg daridorexant.
Group II: Treatment A (5 × 10 mg daridorexant)Experimental Treatment1 Intervention
Participants will receive a single oral dose of 5 × 10 mg daridorexant.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Daridorexant 25 mg
2023
Completed Phase 3
~1810
Daridorexant 10 mg
2023
Completed Phase 3
~850

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Idorsia Pharmaceuticals Ltd.Lead Sponsor
121 Previous Clinical Trials
35,925 Total Patients Enrolled
Clinical Trials Study DirectorStudy DirectorIdosia Pharmaceuticals Ltd
3 Previous Clinical Trials
2,904 Total Patients Enrolled
~15 spots leftby Jan 2026