~15 spots leftby Mar 2026

PCNA Inhibitor AOH1996 for Cancer

Recruiting in Palo Alto (17 mi)
Overseen ByVincent Chung
Age: 18+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: Phase 1
Waitlist Available
Sponsor: City of Hope Medical Center
No Placebo Group

Trial Summary

What is the purpose of this trial?This trial tests AOH1996, a drug that may stop cancer cell growth by blocking essential enzymes. It targets patients with solid tumors that haven't responded to standard treatments.

Eligibility Criteria

Participant Groups

1Treatment groups
Experimental Treatment
Group I: Treatment (PCNA inhibitor AOH1996)Experimental Treatment1 Intervention
Patients receive PCNA inhibitor AOH1996 PO BID on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.

Find A Clinic Near You

Research locations nearbySelect from list below to view details:
Honor Health Research and Innovation InstituteScottsdale, AZ
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Who is running the clinical trial?

City of Hope Medical CenterLead Sponsor
National Cancer Institute (NCI)Collaborator

References