GD2-targeted CAR T-Cells for Neuroblastoma
Trial Summary
What is the purpose of this trial?
This trial is for patients with certain cancers that have returned or didn't respond to treatment. It uses the patient's own T cells, modified to better fight cancer and survive longer. The goal is to find the safest dose and see how well these modified cells work against cancer. This approach has changed how doctors treat certain types of cancer by using modified T cells to find and destroy cancer cells.
Research Team
Bilal Omer, MD
Principal Investigator
Baylor College of Medicine
Eligibility Criteria
This trial is for people aged 1-75 with certain types of cancer (like neuroblastoma, sarcoma, uveal melanoma, breast cancer) that have a substance called GD2 on their cells. The cancers should be resistant to standard treatments or have come back after treatment. Participants need to be relatively healthy otherwise, with a life expectancy of at least 12 weeks and stable organ function.Inclusion Criteria
Exclusion Criteria
Treatment Details
Interventions
- C7R-GD2.CART cells (CAR T-cell Therapy)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Baylor College of Medicine
Lead Sponsor
Center for Cell and Gene Therapy, Baylor College of Medicine
Collaborator
Cancer Prevention Research Institute of Texas
Collaborator
The Methodist Hospital Research Institute
Collaborator