Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)
Palo Alto (17 mi)Overseen byCaroline O Cobb, PhD
Age: 18 - 65
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: N/A
Waitlist Available
Sponsor: Virginia Commonwealth University
No Placebo Group
Approved in 3 jurisdictions
Trial Summary
What is the purpose of this trial?This trial aims to understand how using e-cigarettes affects behaviors related to addiction by studying the rate at which nicotine is delivered. It focuses on individuals who use e-cigarettes to see if faster or higher nicotine delivery increases the likelihood of addiction.
Eligibility Criteria
Treatment Details
5Treatment groups
Experimental Treatment
Active Control
Group I: ECIG 30 Watts, 8 mg/ml nicotineExperimental Treatment1 Intervention
Group II: ECIG 30 Watts, 30 mg/ml nicotineExperimental Treatment1 Intervention
Group III: ECIG 30 Watts, 15 mg/ml nicotineExperimental Treatment1 Intervention
Group IV: ECIG 30 Watts, 0 mg/ml nicotineExperimental Treatment1 Intervention
Group V: Own Brand CigaretteActive Control1 Intervention
Tobacco product administration and assessment is already approved in United States, European Union, Canada for the following indications:
🇺🇸 Approved in United States as Tobacco products for:
- Nicotine dependence
- Smoking cessation
🇪🇺 Approved in European Union as Nicotine-containing products for:
- Nicotine dependence
- Smoking cessation
🇨🇦 Approved in Canada as Vaping products for:
- Nicotine dependence
- Smoking cessation
Find a clinic near you
Research locations nearbySelect from list below to view details:
Center for the Study of Tobacco ProductsRichmond, VA
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Who is running the clinical trial?
Virginia Commonwealth UniversityLead Sponsor
National Institute on Drug Abuse (NIDA)Collaborator