Lidocaine IV vs. ESP Block for Rib Fractures (Rib Fract ESP Trial)

Phase 2

Waitlist Available

Research Sponsored by Stanford University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

All adult patients admitted to Stanford Health Care with two or more acute traumatic rib fractures.

- All adult patients admitted to Stanford Health Care with two or more acute traumatic rib fractures.

Must not have

Hemodynamically instability

Polytrauma (defined as bone or organ injury outside the thorax)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up every 4 hours general pain scores, and baseline, 24 hours, 48 hour, 72 hours for pain scores with cough and inspiration.

Summary

This trial will compare the effectiveness of ESPB as an alternative method to the current standard of care at Stanford Health Care (SHC) for pain management in traumatic rib fractures.

Who is the study for?

This trial is for adults at Stanford Health Care with two or more acute traumatic rib fractures. It's not for those on mechanical ventilation, with lidocaine allergies or heart conduction problems, chronic opioid users, pregnant women, prisoners, unstable vital signs, or injuries beyond the chest area.

What is being tested?

The study compares pain management methods for rib fractures: continuous intravenous (IV) Lidocaine infusion versus a new nerve block called ESPB. The goal is to see which method better controls pain and improves breathing efforts after injury.

What are the potential side effects?

Possible side effects include allergic reactions to lidocaine such as rash or itching; nervous system issues like dizziness or seizures; and heart-related side effects including changes in blood pressure or irregular heartbeat.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have two or more broken ribs from a recent injury.

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I have two or more broken ribs from a recent injury.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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My blood pressure and heart rate are stable.

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I have injuries to bones or organs outside my chest area.

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I am allergic to local anesthetics or have specific heart conditions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ every 4 hours general pain scores, and baseline, 24 hours, 48 hour, 72 hours for pain scores with cough and inspiration.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~every 4 hours general pain scores, and baseline, 24 hours, 48 hour, 72 hours for pain scores with cough and inspiration.

This trial's timeline: 3 weeks for screening, Varies for treatment, and every 4 hours general pain scores, and baseline, 24 hours, 48 hour, 72 hours for pain scores with cough and inspiration. for reporting.