DOAC vs Warfarin as Blood Thinners After Heart Surgery (DANCE Trial)
Trial Summary
The trial information does not specify if you need to stop taking your current medications. However, since the trial involves comparing different blood thinners, you may need to switch to the study medication.
Research shows that DOACs, like apixaban and rivaroxaban, are safer and more effective than warfarin for preventing strokes in patients with atrial fibrillation, with a lower risk of serious bleeding. This suggests they could be a good option for blood thinning after heart surgery.
12345Research suggests that direct oral anticoagulants (DOACs) like apixaban and rivaroxaban are generally safe and may be safer than warfarin, but they should be used with caution in people with kidney or liver issues. Unlike warfarin, DOACs do not require regular blood tests to monitor their effect, but they lack specific antidotes for reversing their action in case of severe bleeding.
12567DOACs (Direct Oral Anticoagulants) like apixaban and rivaroxaban are easier to manage than warfarin because they don't require regular blood tests to monitor their effect. They also have a lower risk of causing bleeding in the brain, making them a safer option for some patients.
12348Eligibility Criteria
This trial is for adults over 18 who've had open heart surgery within the last 10 days and need blood thinners due to atrial fibrillation. It's not for those with severe kidney or liver disease, ongoing bleeding issues, mechanical heart valves, or women who are pregnant or could become pregnant.Inclusion Criteria
Exclusion Criteria
Participant Groups
- Atrial fibrillation
- Deep vein thrombosis
- Pulmonary embolism
- Venous thromboembolism
- Atrial fibrillation
- Deep vein thrombosis
- Pulmonary embolism
- Venous thromboembolism
- Stroke prevention
- Atrial fibrillation
- Deep vein thrombosis
- Pulmonary embolism
- Venous thromboembolism
- Atrial fibrillation
- Deep vein thrombosis
- Pulmonary embolism
- Venous thromboembolism
- Atrial fibrillation
- Deep vein thrombosis
- Pulmonary embolism
- Venous thromboembolism
- Atrial fibrillation
- Deep vein thrombosis
- Pulmonary embolism
- Venous thromboembolism