Trial Summary
What is the purpose of this trial?This trial is testing a new drug called LY3502970 to see if it can help people who are overweight or have obesity lose weight.
Eligibility Criteria
Treatment Details
7Treatment groups
Experimental Treatment
Placebo Group
Group I: 45 mg-2 LY3502970Experimental Treatment1 Intervention
Participants received maintenance dose 45 mg with dose escalation starting from 2 mg, 3 mg, 6 mg, 12 mg, 24 mg, 36 mg and then 45 mg LY3502970 administered orally once daily until 36 weeks.
Group II: 45 mg-1 LY3502970Experimental Treatment1 Intervention
Participants received maintenance dose 45 mg with dose escalation starting from 3 mg, 6 mg, 8 mg, 12 mg, 24 mg, 36 mg and then 45 mg LY3502970 administered orally once daily until 36 weeks.
Group III: 36 mg-2 LY3502970Experimental Treatment1 Intervention
Participants received maintenance dose 36 mg with dose escalation starting from 3 mg, 6 mg,12 mg, 24 mg and then 36 mg LY3502970 administered orally once daily until 36 weeks.
Group IV: 36 mg-1 LY3502970Experimental Treatment1 Intervention
Participants received maintenance dose 36 mg with dose escalation starting from 2 mg, 3 mg, 6 mg, 8 mg, 12 mg, 24 mg and then 36 mg LY3502970 administered orally once daily until 36 weeks.
Group V: 24 mg LY3502970Experimental Treatment1 Intervention
Participants received maintenance dose 24 mg with dose escalation starting from 3 mg, 6 mg, 8 mg,12 mg and then 24 mg LY3502970 administered orally once daily until 36 weeks.
Group VI: 12 milligram (mg) LY3502970Experimental Treatment1 Intervention
Participants received maintenance dose 12 mg with dose escalation starting from 3 mg,6 mg and then 12 mg LY3502970 administered orally once daily until 36 weeks.
Group VII: PlaceboPlacebo Group1 Intervention
Participants received placebo administered orally once daily until 36 weeks.
Find a clinic near you
Research locations nearbySelect from list below to view details:
Alpha Recherche CliniqueQuebec, Canada
St. Vincent Hospital d/b/a Prevea HealthGreen Bay, WI
Bluewater Clinical Research Group Inc.Sarnia, Canada
Centre Médical et Professionnel de l'Ouest de PortneufSaint Marc des Carrières, Canada
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Who is running the clinical trial?
Eli Lilly and CompanyLead Sponsor