← Back to Search

Opioid Antagonist

Naloxone Hydrochloride Lotion, 0.5% for Cutaneous T-Cell Lymphoma

Phase 3
Waitlist Available
Research Sponsored by Elorac, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and day 14 of each treatment period
Awards & highlights
Pivotal Trial

Summary

This trial will study the safety and effectiveness of a naloxone lotion for treating itchiness in patients with mycosis fungoides or Sézary syndrome, both forms of cutaneous T-cell lymphoma. The study will also see if the drug is absorbed into the bloodstream and, if so, measure the plasma levels reached after two weeks of use.

Eligible Conditions
  • Cutaneous T-Cell Lymphoma
  • Mycosis Fungoides and Sezary Syndrome
  • Mycosis Fungoides

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and day 14 of each treatment period
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and day 14 of each treatment period for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Numeric Rating Scale (NRS) for Pruritus
Secondary study objectives
Categorical Rating Scale (CRS) for Skin Integrity
Numeric Rating Scale for Pruritus
Numeric Rating Scale for Sleep
+2 more

Awards & Highlights

Pivotal Trial
The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Naloxone Hydrochloride Lotion, 0.5%Active Control1 Intervention
Naloxone Hydrochloride Lotion 0.5%
Group II: Placebo LotionPlacebo Group1 Intervention
Placebo Lotion

Find a Location

Who is running the clinical trial?

Elorac, Inc.Lead Sponsor
2 Previous Clinical Trials
127 Total Patients Enrolled
Scott B Phillips, MDStudy DirectorElorac, Inc.
2 Previous Clinical Trials
33 Total Patients Enrolled
~7 spots leftby Dec 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top